Modeling of mutant superoxide dismutase 1 octamers with cross-linked disulfide bonds

Mutant superoxide dismutase 1 (SOD1) may form cyclic structures due to its greater instability from aberrant demetallization and oxidation of cysteine bonds. This cyclic structure may allow SOD1 to form ion channels on membranes such as the mitochondrial membrane, causing imbalances in the concentra...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of molecular modeling 2022-04, Vol.28 (4), p.89-89, Article 89
Hauptverfasser:	Zhang, Aidan, Teigen, Knut, Kouznetsova, Valentina L., Tsigelny, Igor F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Characterization and Evaluation of Materials Chemistry Chemistry and Materials Science Computer Appl. in Life Sciences Computer Applications in Chemistry Crosslinking Demetallization Dimers Dynamic stability Ion channels Membranes Modelling Molecular dynamics Molecular Medicine Molecular structure Original Paper Oxidation Superoxide dismutase Theoretical and Computational Chemistry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!