Artificial Neural Network vs. Pharmacometric Model for Population Prediction of Plasma Concentration in Real‐World Data: A Case Study on Valproic Acid

We compared the predictive performance of an artificial neural network to traditional pharmacometric modeling for population prediction of plasma concentrations of valproate in real‐world data. We included individuals aged 65 years or older with epilepsy who redeemed their first prescription of valp...

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Veröffentlicht in:	Clinical pharmacology and therapeutics 2022-06, Vol.111 (6), p.1278-1285
Hauptverfasser:	Soeorg, Hiie, Sverrisdóttir, Eva, Andersen, Morten, Lund, Trine Meldgaard, Sessa, Maurizio
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Humans Neural Networks, Computer Valproic Acid - therapeutic use
Online-Zugang:	Volltext
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