Conservative management of complicated colonic diverticulitis: long-term results
Background The management of recurrent diverticulitis after initial non-operative treatment remains controversial. Recurrences after medical treatment have been described up to 36% but only 3 to 5% develop complicated disease. Aim To investigate the effectiveness of conservative treatment during a p...
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Veröffentlicht in: | European journal of trauma and emergency surgery (Munich : 2007) 2023-10, Vol.49 (5), p.2225-2233 |
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creator | Perrone, Gennaro Giuffrida, Mario Tarasconi, Antonio Petracca, Gabriele Luciano Annicchiarico, Alfredo Bonati, Elena Rossi, Giorgio Catena, Fausto |
description | Background
The management of recurrent diverticulitis after initial non-operative treatment remains controversial. Recurrences after medical treatment have been described up to 36% but only 3 to 5% develop complicated disease.
Aim
To investigate the effectiveness of conservative treatment during a prolonged follow-up after first episode of complicated diverticulitis.
Methods
This retrospective single-center study describes the conservative management and outcomes of 207 with complicated acute colonic diverticulitis treated at Parma University Hospital from 1 January 2012 until 31 December 2019. The follow-up was performed until December 2020. Diverticulitis severity was staged according to WSES CT driven classification for acute diverticulitis.
Results
We enrolled 207 patients (118 males, 89 females). The mean age was 59 ± 14.5 years. CT scan of the abdomen was always performed. Almost all patients were treated with bowel rest and antibiotics (98.5%). Percutaneous drainage of abscessed diverticulitis was performed 12 times (5.7%). Average follow-up was 48 ± 28.8 months. 79 patients had new episodes of diverticulitis (38.1%) and 23 patients had high severity new episodes (11.1%). 11 patients underwent surgery (7.7%). Lower CT-Stages showed a higher recurrence rate (
P
= 0.002). Grade III diverticulitis showed a lower recurrence rate (
P
= 0.007).
Patients with chronic NSAID use showed a higher incidence of high severity new episodes (
P
= 0.039).
No recurrence rate differences were noted among patients with or without home therapy (
P
> 0.05).
Conclusions
Non-operative treatment is an effective and safe option in selected patients with complicated diverticulitis. The recurrence’s severity is generally lower than the previous episodes and this can justify the conservative management. |
doi_str_mv | 10.1007/s00068-022-01922-1 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2637581020</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2637581020</sourcerecordid><originalsourceid>FETCH-LOGICAL-c375t-199054478d0a3576f92fdd3846f6d8ed7477bf1af430280454a65d917a8035cc3</originalsourceid><addsrcrecordid>eNp9kEtLAzEUhYMotlb_gAsZcONm9OYxScadFF9Q0IWuQ5pkypR51CRT8N-b2lrBhZt7LzffPScchM4xXGMAcRMAgMscCMkBl6niAzTGktO8LBk-3M-UjtBJCMtEAy_IMRrRgnAiGB-j12nfBefXOtZrl7W60wvXui5mfZWZvl01tdHR2TQ3fVebzCbMx9oMTR3rcJul7SKPzreZd2FoYjhFR5Vugjvb9Ql6f7h_mz7ls5fH5-ndLDdUFDHHZQkFY0Ja0LQQvCpJZS2VjFfcSmcFE2JeYV0xCkQCK5jmhS2x0BJoYQydoKut7sr3H4MLUbV1MK5pdOf6ISjCk4_EQCChl3_QZT_4Lv1OEcklS158Q5EtZXwfgneVWvm61f5TYVCbvNU2b5XyVt95K5yOLnbSw7x1dn_yE3AC6BYI6albOP_r_Y_sF7X2ilo</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2868474760</pqid></control><display><type>article</type><title>Conservative management of complicated colonic diverticulitis: long-term results</title><source>SpringerLink Journals - AutoHoldings</source><creator>Perrone, Gennaro ; Giuffrida, Mario ; Tarasconi, Antonio ; Petracca, Gabriele Luciano ; Annicchiarico, Alfredo ; Bonati, Elena ; Rossi, Giorgio ; Catena, Fausto</creator><creatorcontrib>Perrone, Gennaro ; Giuffrida, Mario ; Tarasconi, Antonio ; Petracca, Gabriele Luciano ; Annicchiarico, Alfredo ; Bonati, Elena ; Rossi, Giorgio ; Catena, Fausto</creatorcontrib><description>Background
The management of recurrent diverticulitis after initial non-operative treatment remains controversial. Recurrences after medical treatment have been described up to 36% but only 3 to 5% develop complicated disease.
Aim
To investigate the effectiveness of conservative treatment during a prolonged follow-up after first episode of complicated diverticulitis.
Methods
This retrospective single-center study describes the conservative management and outcomes of 207 with complicated acute colonic diverticulitis treated at Parma University Hospital from 1 January 2012 until 31 December 2019. The follow-up was performed until December 2020. Diverticulitis severity was staged according to WSES CT driven classification for acute diverticulitis.
Results
We enrolled 207 patients (118 males, 89 females). The mean age was 59 ± 14.5 years. CT scan of the abdomen was always performed. Almost all patients were treated with bowel rest and antibiotics (98.5%). Percutaneous drainage of abscessed diverticulitis was performed 12 times (5.7%). Average follow-up was 48 ± 28.8 months. 79 patients had new episodes of diverticulitis (38.1%) and 23 patients had high severity new episodes (11.1%). 11 patients underwent surgery (7.7%). Lower CT-Stages showed a higher recurrence rate (
P
= 0.002). Grade III diverticulitis showed a lower recurrence rate (
P
= 0.007).
Patients with chronic NSAID use showed a higher incidence of high severity new episodes (
P
= 0.039).
No recurrence rate differences were noted among patients with or without home therapy (
P
> 0.05).
Conclusions
Non-operative treatment is an effective and safe option in selected patients with complicated diverticulitis. The recurrence’s severity is generally lower than the previous episodes and this can justify the conservative management.</description><identifier>ISSN: 1863-9933</identifier><identifier>EISSN: 1863-9941</identifier><identifier>DOI: 10.1007/s00068-022-01922-1</identifier><identifier>PMID: 35262746</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Antibiotics ; Clinical outcomes ; Critical Care Medicine ; Diverticulitis ; Emergency Medicine ; Intensive ; Medical treatment ; Medicine ; Medicine & Public Health ; Original Article ; Sports Medicine ; Surgery ; Surgical Orthopedics ; Traumatic Surgery</subject><ispartof>European journal of trauma and emergency surgery (Munich : 2007), 2023-10, Vol.49 (5), p.2225-2233</ispartof><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany 2022</rights><rights>2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany.</rights><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany 2022.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-199054478d0a3576f92fdd3846f6d8ed7477bf1af430280454a65d917a8035cc3</citedby><cites>FETCH-LOGICAL-c375t-199054478d0a3576f92fdd3846f6d8ed7477bf1af430280454a65d917a8035cc3</cites><orcidid>0000-0001-8335-3941</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00068-022-01922-1$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00068-022-01922-1$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35262746$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Perrone, Gennaro</creatorcontrib><creatorcontrib>Giuffrida, Mario</creatorcontrib><creatorcontrib>Tarasconi, Antonio</creatorcontrib><creatorcontrib>Petracca, Gabriele Luciano</creatorcontrib><creatorcontrib>Annicchiarico, Alfredo</creatorcontrib><creatorcontrib>Bonati, Elena</creatorcontrib><creatorcontrib>Rossi, Giorgio</creatorcontrib><creatorcontrib>Catena, Fausto</creatorcontrib><title>Conservative management of complicated colonic diverticulitis: long-term results</title><title>European journal of trauma and emergency surgery (Munich : 2007)</title><addtitle>Eur J Trauma Emerg Surg</addtitle><addtitle>Eur J Trauma Emerg Surg</addtitle><description>Background
The management of recurrent diverticulitis after initial non-operative treatment remains controversial. Recurrences after medical treatment have been described up to 36% but only 3 to 5% develop complicated disease.
Aim
To investigate the effectiveness of conservative treatment during a prolonged follow-up after first episode of complicated diverticulitis.
Methods
This retrospective single-center study describes the conservative management and outcomes of 207 with complicated acute colonic diverticulitis treated at Parma University Hospital from 1 January 2012 until 31 December 2019. The follow-up was performed until December 2020. Diverticulitis severity was staged according to WSES CT driven classification for acute diverticulitis.
Results
We enrolled 207 patients (118 males, 89 females). The mean age was 59 ± 14.5 years. CT scan of the abdomen was always performed. Almost all patients were treated with bowel rest and antibiotics (98.5%). Percutaneous drainage of abscessed diverticulitis was performed 12 times (5.7%). Average follow-up was 48 ± 28.8 months. 79 patients had new episodes of diverticulitis (38.1%) and 23 patients had high severity new episodes (11.1%). 11 patients underwent surgery (7.7%). Lower CT-Stages showed a higher recurrence rate (
P
= 0.002). Grade III diverticulitis showed a lower recurrence rate (
P
= 0.007).
Patients with chronic NSAID use showed a higher incidence of high severity new episodes (
P
= 0.039).
No recurrence rate differences were noted among patients with or without home therapy (
P
> 0.05).
Conclusions
Non-operative treatment is an effective and safe option in selected patients with complicated diverticulitis. The recurrence’s severity is generally lower than the previous episodes and this can justify the conservative management.</description><subject>Antibiotics</subject><subject>Clinical outcomes</subject><subject>Critical Care Medicine</subject><subject>Diverticulitis</subject><subject>Emergency Medicine</subject><subject>Intensive</subject><subject>Medical treatment</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Original Article</subject><subject>Sports Medicine</subject><subject>Surgery</subject><subject>Surgical Orthopedics</subject><subject>Traumatic Surgery</subject><issn>1863-9933</issn><issn>1863-9941</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9kEtLAzEUhYMotlb_gAsZcONm9OYxScadFF9Q0IWuQ5pkypR51CRT8N-b2lrBhZt7LzffPScchM4xXGMAcRMAgMscCMkBl6niAzTGktO8LBk-3M-UjtBJCMtEAy_IMRrRgnAiGB-j12nfBefXOtZrl7W60wvXui5mfZWZvl01tdHR2TQ3fVebzCbMx9oMTR3rcJul7SKPzreZd2FoYjhFR5Vugjvb9Ql6f7h_mz7ls5fH5-ndLDdUFDHHZQkFY0Ja0LQQvCpJZS2VjFfcSmcFE2JeYV0xCkQCK5jmhS2x0BJoYQydoKut7sr3H4MLUbV1MK5pdOf6ISjCk4_EQCChl3_QZT_4Lv1OEcklS158Q5EtZXwfgneVWvm61f5TYVCbvNU2b5XyVt95K5yOLnbSw7x1dn_yE3AC6BYI6albOP_r_Y_sF7X2ilo</recordid><startdate>20231001</startdate><enddate>20231001</enddate><creator>Perrone, Gennaro</creator><creator>Giuffrida, Mario</creator><creator>Tarasconi, Antonio</creator><creator>Petracca, Gabriele Luciano</creator><creator>Annicchiarico, Alfredo</creator><creator>Bonati, Elena</creator><creator>Rossi, Giorgio</creator><creator>Catena, Fausto</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-8335-3941</orcidid></search><sort><creationdate>20231001</creationdate><title>Conservative management of complicated colonic diverticulitis: long-term results</title><author>Perrone, Gennaro ; Giuffrida, Mario ; Tarasconi, Antonio ; Petracca, Gabriele Luciano ; Annicchiarico, Alfredo ; Bonati, Elena ; Rossi, Giorgio ; Catena, Fausto</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-199054478d0a3576f92fdd3846f6d8ed7477bf1af430280454a65d917a8035cc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Antibiotics</topic><topic>Clinical outcomes</topic><topic>Critical Care Medicine</topic><topic>Diverticulitis</topic><topic>Emergency Medicine</topic><topic>Intensive</topic><topic>Medical treatment</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Original Article</topic><topic>Sports Medicine</topic><topic>Surgery</topic><topic>Surgical Orthopedics</topic><topic>Traumatic Surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Perrone, Gennaro</creatorcontrib><creatorcontrib>Giuffrida, Mario</creatorcontrib><creatorcontrib>Tarasconi, Antonio</creatorcontrib><creatorcontrib>Petracca, Gabriele Luciano</creatorcontrib><creatorcontrib>Annicchiarico, Alfredo</creatorcontrib><creatorcontrib>Bonati, Elena</creatorcontrib><creatorcontrib>Rossi, Giorgio</creatorcontrib><creatorcontrib>Catena, Fausto</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of trauma and emergency surgery (Munich : 2007)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Perrone, Gennaro</au><au>Giuffrida, Mario</au><au>Tarasconi, Antonio</au><au>Petracca, Gabriele Luciano</au><au>Annicchiarico, Alfredo</au><au>Bonati, Elena</au><au>Rossi, Giorgio</au><au>Catena, Fausto</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Conservative management of complicated colonic diverticulitis: long-term results</atitle><jtitle>European journal of trauma and emergency surgery (Munich : 2007)</jtitle><stitle>Eur J Trauma Emerg Surg</stitle><addtitle>Eur J Trauma Emerg Surg</addtitle><date>2023-10-01</date><risdate>2023</risdate><volume>49</volume><issue>5</issue><spage>2225</spage><epage>2233</epage><pages>2225-2233</pages><issn>1863-9933</issn><eissn>1863-9941</eissn><abstract>Background
The management of recurrent diverticulitis after initial non-operative treatment remains controversial. Recurrences after medical treatment have been described up to 36% but only 3 to 5% develop complicated disease.
Aim
To investigate the effectiveness of conservative treatment during a prolonged follow-up after first episode of complicated diverticulitis.
Methods
This retrospective single-center study describes the conservative management and outcomes of 207 with complicated acute colonic diverticulitis treated at Parma University Hospital from 1 January 2012 until 31 December 2019. The follow-up was performed until December 2020. Diverticulitis severity was staged according to WSES CT driven classification for acute diverticulitis.
Results
We enrolled 207 patients (118 males, 89 females). The mean age was 59 ± 14.5 years. CT scan of the abdomen was always performed. Almost all patients were treated with bowel rest and antibiotics (98.5%). Percutaneous drainage of abscessed diverticulitis was performed 12 times (5.7%). Average follow-up was 48 ± 28.8 months. 79 patients had new episodes of diverticulitis (38.1%) and 23 patients had high severity new episodes (11.1%). 11 patients underwent surgery (7.7%). Lower CT-Stages showed a higher recurrence rate (
P
= 0.002). Grade III diverticulitis showed a lower recurrence rate (
P
= 0.007).
Patients with chronic NSAID use showed a higher incidence of high severity new episodes (
P
= 0.039).
No recurrence rate differences were noted among patients with or without home therapy (
P
> 0.05).
Conclusions
Non-operative treatment is an effective and safe option in selected patients with complicated diverticulitis. The recurrence’s severity is generally lower than the previous episodes and this can justify the conservative management.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>35262746</pmid><doi>10.1007/s00068-022-01922-1</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0001-8335-3941</orcidid></addata></record> |
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language | eng |
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source | SpringerLink Journals - AutoHoldings |
subjects | Antibiotics Clinical outcomes Critical Care Medicine Diverticulitis Emergency Medicine Intensive Medical treatment Medicine Medicine & Public Health Original Article Sports Medicine Surgery Surgical Orthopedics Traumatic Surgery |
title | Conservative management of complicated colonic diverticulitis: long-term results |
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