Conservative management of complicated colonic diverticulitis: long-term results

Background The management of recurrent diverticulitis after initial non-operative treatment remains controversial. Recurrences after medical treatment have been described up to 36% but only 3 to 5% develop complicated disease. Aim To investigate the effectiveness of conservative treatment during a p...

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Veröffentlicht in:European journal of trauma and emergency surgery (Munich : 2007) 2023-10, Vol.49 (5), p.2225-2233
Hauptverfasser: Perrone, Gennaro, Giuffrida, Mario, Tarasconi, Antonio, Petracca, Gabriele Luciano, Annicchiarico, Alfredo, Bonati, Elena, Rossi, Giorgio, Catena, Fausto
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container_issue 5
container_start_page 2225
container_title European journal of trauma and emergency surgery (Munich : 2007)
container_volume 49
creator Perrone, Gennaro
Giuffrida, Mario
Tarasconi, Antonio
Petracca, Gabriele Luciano
Annicchiarico, Alfredo
Bonati, Elena
Rossi, Giorgio
Catena, Fausto
description Background The management of recurrent diverticulitis after initial non-operative treatment remains controversial. Recurrences after medical treatment have been described up to 36% but only 3 to 5% develop complicated disease. Aim To investigate the effectiveness of conservative treatment during a prolonged follow-up after first episode of complicated diverticulitis. Methods This retrospective single-center study describes the conservative management and outcomes of 207 with complicated acute colonic diverticulitis treated at Parma University Hospital from 1 January 2012 until 31 December 2019. The follow-up was performed until December 2020. Diverticulitis severity was staged according to WSES CT driven classification for acute diverticulitis. Results We enrolled 207 patients (118 males, 89 females). The mean age was 59 ± 14.5 years. CT scan of the abdomen was always performed. Almost all patients were treated with bowel rest and antibiotics (98.5%). Percutaneous drainage of abscessed diverticulitis was performed 12 times (5.7%). Average follow-up was 48 ± 28.8 months. 79 patients had new episodes of diverticulitis (38.1%) and 23 patients had high severity new episodes (11.1%). 11 patients underwent surgery (7.7%). Lower CT-Stages showed a higher recurrence rate ( P  = 0.002). Grade III diverticulitis showed a lower recurrence rate ( P  = 0.007). Patients with chronic NSAID use showed a higher incidence of high severity new episodes ( P  = 0.039). No recurrence rate differences were noted among patients with or without home therapy ( P  > 0.05). Conclusions Non-operative treatment is an effective and safe option in selected patients with complicated diverticulitis. The recurrence’s severity is generally lower than the previous episodes and this can justify the conservative management.
doi_str_mv 10.1007/s00068-022-01922-1
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Recurrences after medical treatment have been described up to 36% but only 3 to 5% develop complicated disease. Aim To investigate the effectiveness of conservative treatment during a prolonged follow-up after first episode of complicated diverticulitis. Methods This retrospective single-center study describes the conservative management and outcomes of 207 with complicated acute colonic diverticulitis treated at Parma University Hospital from 1 January 2012 until 31 December 2019. The follow-up was performed until December 2020. Diverticulitis severity was staged according to WSES CT driven classification for acute diverticulitis. Results We enrolled 207 patients (118 males, 89 females). The mean age was 59 ± 14.5 years. CT scan of the abdomen was always performed. Almost all patients were treated with bowel rest and antibiotics (98.5%). Percutaneous drainage of abscessed diverticulitis was performed 12 times (5.7%). Average follow-up was 48 ± 28.8 months. 79 patients had new episodes of diverticulitis (38.1%) and 23 patients had high severity new episodes (11.1%). 11 patients underwent surgery (7.7%). Lower CT-Stages showed a higher recurrence rate ( P  = 0.002). Grade III diverticulitis showed a lower recurrence rate ( P  = 0.007). Patients with chronic NSAID use showed a higher incidence of high severity new episodes ( P  = 0.039). No recurrence rate differences were noted among patients with or without home therapy ( P  &gt; 0.05). Conclusions Non-operative treatment is an effective and safe option in selected patients with complicated diverticulitis. 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Recurrences after medical treatment have been described up to 36% but only 3 to 5% develop complicated disease. Aim To investigate the effectiveness of conservative treatment during a prolonged follow-up after first episode of complicated diverticulitis. Methods This retrospective single-center study describes the conservative management and outcomes of 207 with complicated acute colonic diverticulitis treated at Parma University Hospital from 1 January 2012 until 31 December 2019. The follow-up was performed until December 2020. Diverticulitis severity was staged according to WSES CT driven classification for acute diverticulitis. Results We enrolled 207 patients (118 males, 89 females). The mean age was 59 ± 14.5 years. CT scan of the abdomen was always performed. Almost all patients were treated with bowel rest and antibiotics (98.5%). Percutaneous drainage of abscessed diverticulitis was performed 12 times (5.7%). Average follow-up was 48 ± 28.8 months. 79 patients had new episodes of diverticulitis (38.1%) and 23 patients had high severity new episodes (11.1%). 11 patients underwent surgery (7.7%). Lower CT-Stages showed a higher recurrence rate ( P  = 0.002). Grade III diverticulitis showed a lower recurrence rate ( P  = 0.007). Patients with chronic NSAID use showed a higher incidence of high severity new episodes ( P  = 0.039). No recurrence rate differences were noted among patients with or without home therapy ( P  &gt; 0.05). Conclusions Non-operative treatment is an effective and safe option in selected patients with complicated diverticulitis. 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Recurrences after medical treatment have been described up to 36% but only 3 to 5% develop complicated disease. Aim To investigate the effectiveness of conservative treatment during a prolonged follow-up after first episode of complicated diverticulitis. Methods This retrospective single-center study describes the conservative management and outcomes of 207 with complicated acute colonic diverticulitis treated at Parma University Hospital from 1 January 2012 until 31 December 2019. The follow-up was performed until December 2020. Diverticulitis severity was staged according to WSES CT driven classification for acute diverticulitis. Results We enrolled 207 patients (118 males, 89 females). The mean age was 59 ± 14.5 years. CT scan of the abdomen was always performed. Almost all patients were treated with bowel rest and antibiotics (98.5%). Percutaneous drainage of abscessed diverticulitis was performed 12 times (5.7%). Average follow-up was 48 ± 28.8 months. 79 patients had new episodes of diverticulitis (38.1%) and 23 patients had high severity new episodes (11.1%). 11 patients underwent surgery (7.7%). Lower CT-Stages showed a higher recurrence rate ( P  = 0.002). Grade III diverticulitis showed a lower recurrence rate ( P  = 0.007). Patients with chronic NSAID use showed a higher incidence of high severity new episodes ( P  = 0.039). No recurrence rate differences were noted among patients with or without home therapy ( P  &gt; 0.05). Conclusions Non-operative treatment is an effective and safe option in selected patients with complicated diverticulitis. The recurrence’s severity is generally lower than the previous episodes and this can justify the conservative management.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>35262746</pmid><doi>10.1007/s00068-022-01922-1</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0001-8335-3941</orcidid></addata></record>
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subjects Antibiotics
Clinical outcomes
Critical Care Medicine
Diverticulitis
Emergency Medicine
Intensive
Medical treatment
Medicine
Medicine & Public Health
Original Article
Sports Medicine
Surgery
Surgical Orthopedics
Traumatic Surgery
title Conservative management of complicated colonic diverticulitis: long-term results
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