Kidney Hypertrophy in Living Kidney Donors and Their Corresponding Recipients

In this long-term study we compared kidney volume changes and function between living kidney donors and their corresponding recipients via magnetic resonance imaging after 3 to 8 years post transplantation. For measurement of the kidney volume in magnetic resonance imaging images we used 3DSlicer. S...

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Veröffentlicht in:Transplantation proceedings 2022-04, Vol.54 (3), p.627-631
Hauptverfasser: Steden, Kilian, Figiel, Jens, Hoyer, Joachim, Kamalanabhaiah, Sahana R.
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creator Steden, Kilian
Figiel, Jens
Hoyer, Joachim
Kamalanabhaiah, Sahana R.
description In this long-term study we compared kidney volume changes and function between living kidney donors and their corresponding recipients via magnetic resonance imaging after 3 to 8 years post transplantation. For measurement of the kidney volume in magnetic resonance imaging images we used 3DSlicer. Statistical analysis was performed via t test and correlation. A profound volume increase was observed in both transplanted and orthotopic kidney. The volume increase of the orthotopic kidneys was with 58 cm³ ± 23.8 cm³ SD (41%) greater than in the corresponding transplanted kidneys with 43 cm³ ± 36.9 cm³ SD (30%). This study detected a persistent volume increase in both orthotopic and transplanted kidneys after donation. Neither significant increases of hypertension or proteinuria were observable or could be correlated to renal hypertrophy.
doi_str_mv 10.1016/j.transproceed.2021.11.040
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subjects Humans
Hypertrophy
Kidney - diagnostic imaging
Kidney Transplantation - adverse effects
Living Donors
Nephrectomy - adverse effects
Nephrectomy - methods
Tissue Donors
title Kidney Hypertrophy in Living Kidney Donors and Their Corresponding Recipients
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