Diagnosis and management of neutropenia in children: The approach of the Study Group on Neutropenia and Marrow Failure Syndromes of the Pediatric Italian Hemato‐Oncology Association (Associazione Italiana Emato‐Oncologia Pediatrica ‐ AIEOP)
Neutropenia refers to a group of diseases characterized by a reduction in neutrophil levels below the recommended age threshold. The present study aimed to review the diagnosis and management of neutropenia, including a diagnostic toolkit and candidate underlying genes. This study also aimed to revi...
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| Veröffentlicht in: | Pediatric blood & cancer 2022-06, Vol.69 (6), p.e29599-n/a |
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| creator | Fioredda, Francesca Onofrillo, Daniela Farruggia, Piero Barone, Angelica Veltroni, Marinella Notarangelo, Lucia Dora Menna, Giuseppe Russo, Giovanna Martire, Baldassarre Finocchi, Andrea Verzegnassi, Federico Bonanomi, Sonia Ramenghi, Ugo Pillon, Marta Dufour, Carlo |
| description | Neutropenia refers to a group of diseases characterized by a reduction in neutrophil levels below the recommended age threshold. The present study aimed to review the diagnosis and management of neutropenia, including a diagnostic toolkit and candidate underlying genes. This study also aimed to review the progress toward the definition of autoimmune and idiopathic neutropenia rising in infancy or in late childhood but without remission, and provide suggestions for efficient diagnostics, including indications for the bone marrow and genetic testing. The management and treatment protocols for common and unique presentations are also reviewed, providing evidence tailored to a single patient. |
| doi_str_mv | 10.1002/pbc.29599 |
| format | Article |
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| ispartof | Pediatric blood & cancer, 2022-06, Vol.69 (6), p.e29599-n/a |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Bone Marrow Bone Marrow Transplantation Child Children Diagnosis Genetic screening granulocyte colony‐stimulating factor Hematology Humans Italy Leukocytes (neutrophilic) Medical Oncology Neutropenia Neutropenia - diagnosis Neutropenia - therapy Oncology Pediatrics Remission Syndrome |
| title | Diagnosis and management of neutropenia in children: The approach of the Study Group on Neutropenia and Marrow Failure Syndromes of the Pediatric Italian Hemato‐Oncology Association (Associazione Italiana Emato‐Oncologia Pediatrica ‐ AIEOP) |
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