Development and in vitro assessment of a bi-layered chitosan-nano-hydroxyapatite osteochondral scaffold

An innovative approach was developed to engineer a multi-layered chitosan scaffold for osteochondral defect repair. A combination of freeze drying and porogen-leaching out methods produced a porous, bioresorbable scaffold with a distinct gradient of pore size (mean = 160–275 μm). Incorporation of 70...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Carbohydrate polymers 2022-04, Vol.282, p.119126-119126, Article 119126
Hauptverfasser:	Pitrolino, Katherine A., Felfel, Reda M., Pellizzeri, Laura Macri, McLaren, Jane, Popov, Alexander A., Sottile, Virginie, Scotchford, Colin A., Scammell, Brigitte E., Roberts, George A.F., Grant, David M.
Format:	Artikel
Sprache:	eng
Schlagworte:	arthroscopy bone formation cartilage Cell Differentiation Cell Proliferation cell structures Cells, Cultured Chitosan Chondrogenesis Durapatite Graded porosity Humans Mesenchymal stem cells Mesenchymal Stem Cells - cytology Mesenchymal Stem Cells - metabolism Microspheres Nano-hydroxyapatite Nanostructures Osteochondral scaffold Osteogenesis Polyesters porosity Tensile Strength Tissue engineering Tissue Scaffolds
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!