Chemical manipulation of plant water use
[Display omitted] Agricultural productivity is dictated by water availability and consequently drought is the major source of crop losses worldwide. The phytohormone abscisic acid (ABA) is elevated in response to water deficit and modulates drought tolerance by reducing water consumption and inducin...
Gespeichert in:
| Veröffentlicht in: | Bioorganic & medicinal chemistry 2016-02, Vol.24 (3), p.493-500 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 500 |
|---|---|
| container_issue | 3 |
| container_start_page | 493 |
| container_title | Bioorganic & medicinal chemistry |
| container_volume | 24 |
| creator | Helander, Jonathan D.M. Vaidya, Aditya S. Cutler, Sean R. |
| description | [Display omitted]
Agricultural productivity is dictated by water availability and consequently drought is the major source of crop losses worldwide. The phytohormone abscisic acid (ABA) is elevated in response to water deficit and modulates drought tolerance by reducing water consumption and inducing other drought-protective responses. The recent identification of ABA receptors, elucidation of their structures and understanding of the core ABA signaling network has created new opportunities for agrochemical development. An unusually large gene family encodes ABA receptors and, until recently, it was unclear if selective or pan-agonists would be necessary for modulating water use. The recent identification of the selective agonist quinabactin has resolved this issue and defined Pyrabactin Resistance 1 (PYR1) and its close relatives as key targets for water use control. This review provides an overview of the structure and function of ABA receptors, progress in the development of synthetic agonists, and the use of orthogonal receptors to enable agrochemical control in transgenic plants. |
| doi_str_mv | 10.1016/j.bmc.2015.11.010 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2636463997</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0968089615301358</els_id><sourcerecordid>1768584129</sourcerecordid><originalsourceid>FETCH-LOGICAL-c462t-13a63cb5ef10d39ce8342aa8f2a7047aa91a8740cfd7e91800f2de9e16d16eed3</originalsourceid><addsrcrecordid>eNqNkDtPwzAURi0EoqXwA1hQRpYEX9t1bDGhipdUiQVmy7VvhKu8iBMQ_55ELYzAdJfzHV0dQs6BZkBBXm2zTeUyRmGZAWQU6AGZg5Ai5VzDIZlTLVVKlZYzchLjllLKhIZjMmNSAsuBz8nl6hWr4GyZVLYO7VDaPjR10hRJW9q6Tz5sj10yRDwlR4UtI57t74K83N0-rx7S9dP94-pmnTohWZ8Ct5K7zRILoJ5rh4oLZq0qmM2pyK3VYFUuqCt8jhoUpQXzqBGkB4no-YJc7rxt17wNGHtTheiwHL_BZoiGSS6F5Frnf6KQS7VUApj-Dzp1yvlkhR3quibGDgvTdqGy3acBaqbsZmvG7GbKbgDMmH3cXOz1w6ZC_7P47jwC1zsAx3TvATsTXcDaoQ8dut74Jvyi_wKA3pBS</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1760896737</pqid></control><display><type>article</type><title>Chemical manipulation of plant water use</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Helander, Jonathan D.M. ; Vaidya, Aditya S. ; Cutler, Sean R.</creator><creatorcontrib>Helander, Jonathan D.M. ; Vaidya, Aditya S. ; Cutler, Sean R.</creatorcontrib><description>[Display omitted]
Agricultural productivity is dictated by water availability and consequently drought is the major source of crop losses worldwide. The phytohormone abscisic acid (ABA) is elevated in response to water deficit and modulates drought tolerance by reducing water consumption and inducing other drought-protective responses. The recent identification of ABA receptors, elucidation of their structures and understanding of the core ABA signaling network has created new opportunities for agrochemical development. An unusually large gene family encodes ABA receptors and, until recently, it was unclear if selective or pan-agonists would be necessary for modulating water use. The recent identification of the selective agonist quinabactin has resolved this issue and defined Pyrabactin Resistance 1 (PYR1) and its close relatives as key targets for water use control. This review provides an overview of the structure and function of ABA receptors, progress in the development of synthetic agonists, and the use of orthogonal receptors to enable agrochemical control in transgenic plants.</description><identifier>ISSN: 0968-0896</identifier><identifier>EISSN: 1464-3391</identifier><identifier>DOI: 10.1016/j.bmc.2015.11.010</identifier><identifier>PMID: 26612713</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Abscisic acid ; Abscisic Acid - metabolism ; Agonist ; agonists ; Agrochemicals - pharmacology ; Arabidopsis Proteins - agonists ; Arabidopsis Proteins - chemistry ; Arabidopsis Proteins - metabolism ; chemistry ; Drought ; drought tolerance ; genes ; Membrane Transport Proteins - agonists ; Membrane Transport Proteins - chemistry ; Membrane Transport Proteins - metabolism ; Plants - drug effects ; Plants - metabolism ; Quinolones - pharmacology ; Receptor ; Sulfonamides - pharmacology ; Water - metabolism</subject><ispartof>Bioorganic & medicinal chemistry, 2016-02, Vol.24 (3), p.493-500</ispartof><rights>2015 The Authors</rights><rights>Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c462t-13a63cb5ef10d39ce8342aa8f2a7047aa91a8740cfd7e91800f2de9e16d16eed3</citedby><cites>FETCH-LOGICAL-c462t-13a63cb5ef10d39ce8342aa8f2a7047aa91a8740cfd7e91800f2de9e16d16eed3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0968089615301358$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26612713$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Helander, Jonathan D.M.</creatorcontrib><creatorcontrib>Vaidya, Aditya S.</creatorcontrib><creatorcontrib>Cutler, Sean R.</creatorcontrib><title>Chemical manipulation of plant water use</title><title>Bioorganic & medicinal chemistry</title><addtitle>Bioorg Med Chem</addtitle><description>[Display omitted]
Agricultural productivity is dictated by water availability and consequently drought is the major source of crop losses worldwide. The phytohormone abscisic acid (ABA) is elevated in response to water deficit and modulates drought tolerance by reducing water consumption and inducing other drought-protective responses. The recent identification of ABA receptors, elucidation of their structures and understanding of the core ABA signaling network has created new opportunities for agrochemical development. An unusually large gene family encodes ABA receptors and, until recently, it was unclear if selective or pan-agonists would be necessary for modulating water use. The recent identification of the selective agonist quinabactin has resolved this issue and defined Pyrabactin Resistance 1 (PYR1) and its close relatives as key targets for water use control. This review provides an overview of the structure and function of ABA receptors, progress in the development of synthetic agonists, and the use of orthogonal receptors to enable agrochemical control in transgenic plants.</description><subject>Abscisic acid</subject><subject>Abscisic Acid - metabolism</subject><subject>Agonist</subject><subject>agonists</subject><subject>Agrochemicals - pharmacology</subject><subject>Arabidopsis Proteins - agonists</subject><subject>Arabidopsis Proteins - chemistry</subject><subject>Arabidopsis Proteins - metabolism</subject><subject>chemistry</subject><subject>Drought</subject><subject>drought tolerance</subject><subject>genes</subject><subject>Membrane Transport Proteins - agonists</subject><subject>Membrane Transport Proteins - chemistry</subject><subject>Membrane Transport Proteins - metabolism</subject><subject>Plants - drug effects</subject><subject>Plants - metabolism</subject><subject>Quinolones - pharmacology</subject><subject>Receptor</subject><subject>Sulfonamides - pharmacology</subject><subject>Water - metabolism</subject><issn>0968-0896</issn><issn>1464-3391</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkDtPwzAURi0EoqXwA1hQRpYEX9t1bDGhipdUiQVmy7VvhKu8iBMQ_55ELYzAdJfzHV0dQs6BZkBBXm2zTeUyRmGZAWQU6AGZg5Ai5VzDIZlTLVVKlZYzchLjllLKhIZjMmNSAsuBz8nl6hWr4GyZVLYO7VDaPjR10hRJW9q6Tz5sj10yRDwlR4UtI57t74K83N0-rx7S9dP94-pmnTohWZ8Ct5K7zRILoJ5rh4oLZq0qmM2pyK3VYFUuqCt8jhoUpQXzqBGkB4no-YJc7rxt17wNGHtTheiwHL_BZoiGSS6F5Frnf6KQS7VUApj-Dzp1yvlkhR3quibGDgvTdqGy3acBaqbsZmvG7GbKbgDMmH3cXOz1w6ZC_7P47jwC1zsAx3TvATsTXcDaoQ8dut74Jvyi_wKA3pBS</recordid><startdate>20160201</startdate><enddate>20160201</enddate><creator>Helander, Jonathan D.M.</creator><creator>Vaidya, Aditya S.</creator><creator>Cutler, Sean R.</creator><general>Elsevier Ltd</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>7S9</scope><scope>L.6</scope></search><sort><creationdate>20160201</creationdate><title>Chemical manipulation of plant water use</title><author>Helander, Jonathan D.M. ; Vaidya, Aditya S. ; Cutler, Sean R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c462t-13a63cb5ef10d39ce8342aa8f2a7047aa91a8740cfd7e91800f2de9e16d16eed3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Abscisic acid</topic><topic>Abscisic Acid - metabolism</topic><topic>Agonist</topic><topic>agonists</topic><topic>Agrochemicals - pharmacology</topic><topic>Arabidopsis Proteins - agonists</topic><topic>Arabidopsis Proteins - chemistry</topic><topic>Arabidopsis Proteins - metabolism</topic><topic>chemistry</topic><topic>Drought</topic><topic>drought tolerance</topic><topic>genes</topic><topic>Membrane Transport Proteins - agonists</topic><topic>Membrane Transport Proteins - chemistry</topic><topic>Membrane Transport Proteins - metabolism</topic><topic>Plants - drug effects</topic><topic>Plants - metabolism</topic><topic>Quinolones - pharmacology</topic><topic>Receptor</topic><topic>Sulfonamides - pharmacology</topic><topic>Water - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Helander, Jonathan D.M.</creatorcontrib><creatorcontrib>Vaidya, Aditya S.</creatorcontrib><creatorcontrib>Cutler, Sean R.</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>AGRICOLA</collection><collection>AGRICOLA - Academic</collection><jtitle>Bioorganic & medicinal chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Helander, Jonathan D.M.</au><au>Vaidya, Aditya S.</au><au>Cutler, Sean R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Chemical manipulation of plant water use</atitle><jtitle>Bioorganic & medicinal chemistry</jtitle><addtitle>Bioorg Med Chem</addtitle><date>2016-02-01</date><risdate>2016</risdate><volume>24</volume><issue>3</issue><spage>493</spage><epage>500</epage><pages>493-500</pages><issn>0968-0896</issn><eissn>1464-3391</eissn><abstract>[Display omitted]
Agricultural productivity is dictated by water availability and consequently drought is the major source of crop losses worldwide. The phytohormone abscisic acid (ABA) is elevated in response to water deficit and modulates drought tolerance by reducing water consumption and inducing other drought-protective responses. The recent identification of ABA receptors, elucidation of their structures and understanding of the core ABA signaling network has created new opportunities for agrochemical development. An unusually large gene family encodes ABA receptors and, until recently, it was unclear if selective or pan-agonists would be necessary for modulating water use. The recent identification of the selective agonist quinabactin has resolved this issue and defined Pyrabactin Resistance 1 (PYR1) and its close relatives as key targets for water use control. This review provides an overview of the structure and function of ABA receptors, progress in the development of synthetic agonists, and the use of orthogonal receptors to enable agrochemical control in transgenic plants.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>26612713</pmid><doi>10.1016/j.bmc.2015.11.010</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0968-0896 |
| ispartof | Bioorganic & medicinal chemistry, 2016-02, Vol.24 (3), p.493-500 |
| issn | 0968-0896 1464-3391 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2636463997 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Abscisic acid Abscisic Acid - metabolism Agonist agonists Agrochemicals - pharmacology Arabidopsis Proteins - agonists Arabidopsis Proteins - chemistry Arabidopsis Proteins - metabolism chemistry Drought drought tolerance genes Membrane Transport Proteins - agonists Membrane Transport Proteins - chemistry Membrane Transport Proteins - metabolism Plants - drug effects Plants - metabolism Quinolones - pharmacology Receptor Sulfonamides - pharmacology Water - metabolism |
| title | Chemical manipulation of plant water use |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-07T11%3A12%3A33IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Chemical%20manipulation%20of%20plant%20water%20use&rft.jtitle=Bioorganic%20&%20medicinal%20chemistry&rft.au=Helander,%20Jonathan%20D.M.&rft.date=2016-02-01&rft.volume=24&rft.issue=3&rft.spage=493&rft.epage=500&rft.pages=493-500&rft.issn=0968-0896&rft.eissn=1464-3391&rft_id=info:doi/10.1016/j.bmc.2015.11.010&rft_dat=%3Cproquest_cross%3E1768584129%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1760896737&rft_id=info:pmid/26612713&rft_els_id=S0968089615301358&rfr_iscdi=true |