YY1 PROMOTES MICROGLIA M2 POLARIZATION THROUGH THE MIR-130A-3P/TREM-2 AXIS TO ALLEVIATE SEPSIS-ASSOCIATED ENCEPHALOPATHY

Sepsis-associated encephalopathy (SAE) induces cognitive dysfunction via mechanisms that commonly involve neuroinflammation. Yin Yang 1 (YY1) is an important transcription factor which acts as a key role in sepsis and neuroepithelium development. However, the function of YY1 in SAE remains unclear....

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Veröffentlicht in:Shock (Augusta, Ga.) Ga.), 2022-08, Vol.58 (2), p.128-136
Hauptverfasser: Peng, Liang-Shan, Xu, Yan, Wang, Qiao-Sheng
Format: Artikel
Sprache:eng
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