Effectiveness of crizotinib versus entrectinib in ROS1 -positive non-small-cell lung cancer using clinical and real-world data

To compare clinical trial results for crizotinib and entrectinib in -positive non-small-cell lung cancer and compare clinical trial data and real-world outcomes for crizotinib. We analyzed four phase I-II studies using a simulated treatment comparison (STC). A STC of clinical trial versus real-world...

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Veröffentlicht in:	Future oncology (London, England) England), 2022-06, Vol.18 (17), p.2063-2074
Hauptverfasser:	Tremblay, Gabriel, Groff, Michael, Iadeluca, Laura, Daniele, Patrick, Wilner, Keith, Wiltshire, Robin, Bartolome, Lauren, Usari, Tiziana, Cappelleri, Joseph C, Camidge, D Ross
Format:	Artikel
Sprache:	eng
Schlagworte:	Benzamides - therapeutic use Carcinoma, Non-Small-Cell Lung - drug therapy Carcinoma, Non-Small-Cell Lung - genetics Clinical Trials as Topic Crizotinib - therapeutic use Humans Indazoles - therapeutic use Lung Neoplasms - drug therapy Lung Neoplasms - genetics Protein Kinase Inhibitors - therapeutic use Protein-Tyrosine Kinases - genetics Protein-Tyrosine Kinases - therapeutic use Proto-Oncogene Proteins - genetics Treatment Outcome
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