Hereditary gynecologic tumors and precision cancer medicine

Gynecologic cancers are more often caused by genetic factors than other cancers. Genetic testing has become a promising avenue for the prevention, prognosis, and treatment of cancers. This review describes molecular features of gynecologic tumors linked to hereditary syndromes, gives an overview of...

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Veröffentlicht in:	The journal of obstetrics and gynaecology research 2022-05, Vol.48 (5), p.1076-1090
Hauptverfasser:	Ogawa, Chikako, Hirasawa, Akira, Ida, Naoyuki, Nakamura, Keiichiro, Masuyama, Hisashi
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast cancer Cancer Colorectal cancer Colorectal Neoplasms, Hereditary Nonpolyposis - diagnosis Colorectal Neoplasms, Hereditary Nonpolyposis - genetics Colorectal Neoplasms, Hereditary Nonpolyposis - therapy Cowden syndrome Female Genetic disorders Genetic diversity Genetic factors Genetic Predisposition to Disease Genetic screening Genetic Testing Genital Neoplasms, Female - genetics Genital Neoplasms, Female - therapy Gynecology hereditary breast and ovarian cancer syndrome homologous recombination deficiency Humans Lynch syndrome multigene panel testing Neoplastic Syndromes, Hereditary - diagnosis Neoplastic Syndromes, Hereditary - genetics Neoplastic Syndromes, Hereditary - therapy Ovarian cancer Peutz–Jeghers syndrome Risk assessment Targeted cancer therapy Tumors
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