Copper-Catalyzed Divergent C–H Functionalization Reaction of Quinoxalin-2(1H)‑ones and Alkynes Controlled by N1-Substituents for the Synthesis of (Z)‑Enaminones and Furo[2,3‑b]quinoxalines

With control by N1-substituents, the switchable divergent C–H functionalization reaction of quinoxalin-2­(1H)-ones is achieved for the synthesis of (Z)-enaminones and furo­[2,3-b]­quinoxalines using the combination of a copper catalyst and an oxidant. This new protocol features mild reaction conditi...

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Veröffentlicht in:	Organic letters 2022-03, Vol.24 (9), p.1859-1864
Hauptverfasser:	Yang, Guang, Xiong, Zhicheng, Nie, Hongsheng, He, Meiqin, Feng, Qiong, Li, Xuan, Huang, Huabin, Wang, Shoucai, Ji, Fanghua, Jiang, Guangbin
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkynes Catalysis Copper HeLa Cells Humans Molecular Structure Quinoxalines - pharmacology
Online-Zugang:	Volltext
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