Unambiguous identification and determination of A234-Novichok nerve agent biomarkers in biological fluids using GC–MS/MS and LC–MS/MS

The present study was intended to develop suitable methods for unambiguous identification and determination of ethyl (1-(diethylamino)ethylidene) phosphoramidofluoridate (known as A234-Novichok) biomarkers in urine and plasma samples. Multiple biomarkers were investigated for the first time, to veri...

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Veröffentlicht in:	Analytical and bioanalytical chemistry 2022-05, Vol.414 (11), p.3429-3442
Hauptverfasser:	Mirbabaei, Fatemeh, Mohammad-Khah, Ali, Naseri, Mohammad Taghi, Babri, Mehran, Faraz, Sajjad Mousavi, Hosseini, Seyyed Esmaeil, Ashrafi, Davood
Format:	Artikel
Sprache:	eng
Schlagworte:	Adducts Albumins Analytical Chemistry Biochemistry Biological markers Biomarkers Blood Butyrylcholinesterase Characterization and Evaluation of Materials Chemical properties Chemical weapons Chemistry Chemistry and Materials Science Chromatography Chromatography, Liquid - methods Food Science Gas chromatography Gas Chromatography-Mass Spectrometry Identification and classification Intoxication Laboratory Medicine Liquid chromatography Mass spectrometry Mass spectroscopy Methods Monitoring/Environmental Analysis Nerve agents Nerve Agents - analysis Nerves Organophosphates Protein adducts Proteins Research Paper Sample preparation Solid phases Tandem Mass Spectrometry - methods
Online-Zugang:	Volltext
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