Meta-analysis of sleep deprivation effects on depression in rodents
•We provide an evaluation of the experimental SD effects on depression in rodents.•We explore the heterogeneous factors that may be associated with outcomes (eg. strains, test method).•We found that SD worsened depression-like behaviors by tail suspension test. To our knowledge, the relationship of...
Gespeichert in:
| Veröffentlicht in: | Brain research 2022-05, Vol.1782, p.147841-147841, Article 147841 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 147841 |
|---|---|
| container_issue | |
| container_start_page | 147841 |
| container_title | Brain research |
| container_volume | 1782 |
| creator | Hu, Baiqi Liu, Chunyan Lv, Tingting Luo, Fangyi Qian, Chao Zhang, Jian Ye, Mengfei Liu, Zheng |
| description | •We provide an evaluation of the experimental SD effects on depression in rodents.•We explore the heterogeneous factors that may be associated with outcomes (eg. strains, test method).•We found that SD worsened depression-like behaviors by tail suspension test.
To our knowledge, the relationship of sleep deprivation (SD) and depression on the rodents remains unclear. In this article, we performed a meta-analysis to provide a comprehensive evaluation of the experimental effects of SD on rodents and explore the heterogeneous factors that may be associated with outcomes.
PubMed, Embase, the Cochrane Library, and Web of Science were searched for articles before January 5th, 2022. The strains of rodents, SD method, and depression measurement tools were recorded. Standardized mean differences based on Hedge’s g were calculated as measures of the effect size.
In total, 19 studies involving 51 trials were included. The overall data suggested that SD had a large effect on exacerbating depression-like behaviors, but there was high heterogeneity [-1.09 (−1.57, −0.62); I2 = 90.3%; P |
| doi_str_mv | 10.1016/j.brainres.2022.147841 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2631624636</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0006899322000658</els_id><sourcerecordid>2631624636</sourcerecordid><originalsourceid>FETCH-LOGICAL-c368t-230e2227536bbe6a0863513f499ccf5c4605472050c7938c90e5499a8a6aa6393</originalsourceid><addsrcrecordid>eNqFkMtOwzAQRS0EoqXwC1WWbFL8SBx7B6p4SUVsYG05zkRylTrFk1bi73FJy5bVaGbuPO4hZM7oglEm79aLOlofIuCCU84XrKhUwc7IlKmK55IX9JxMKaUyV1qLCblCXKdUCE0vyUSUTImSiylZvsFgcxts940es77NsAPYZg1so9_bwfchg7YFN6Rm-C0D4qHqQxb7BsKA1-SitR3CzTHOyOfT48fyJV-9P78uH1a5E1INORcUOOdVKWRdg7RUyfSHaAutnWtLV0haFhWnJXWVFsppCmXqWWWltVJoMSO3495t7L92gIPZeHTQdTZAv0PDpWDJuRQySeUodbFHjNCaZGdj47dh1BwAmrU5ATQHgGYEmAbnxxu7egPN39iJWBLcjwJITvceokHnIThofEyUTNP7_278ACveg6g</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2631624636</pqid></control><display><type>article</type><title>Meta-analysis of sleep deprivation effects on depression in rodents</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><creator>Hu, Baiqi ; Liu, Chunyan ; Lv, Tingting ; Luo, Fangyi ; Qian, Chao ; Zhang, Jian ; Ye, Mengfei ; Liu, Zheng</creator><creatorcontrib>Hu, Baiqi ; Liu, Chunyan ; Lv, Tingting ; Luo, Fangyi ; Qian, Chao ; Zhang, Jian ; Ye, Mengfei ; Liu, Zheng</creatorcontrib><description>•We provide an evaluation of the experimental SD effects on depression in rodents.•We explore the heterogeneous factors that may be associated with outcomes (eg. strains, test method).•We found that SD worsened depression-like behaviors by tail suspension test.
To our knowledge, the relationship of sleep deprivation (SD) and depression on the rodents remains unclear. In this article, we performed a meta-analysis to provide a comprehensive evaluation of the experimental effects of SD on rodents and explore the heterogeneous factors that may be associated with outcomes.
PubMed, Embase, the Cochrane Library, and Web of Science were searched for articles before January 5th, 2022. The strains of rodents, SD method, and depression measurement tools were recorded. Standardized mean differences based on Hedge’s g were calculated as measures of the effect size.
In total, 19 studies involving 51 trials were included. The overall data suggested that SD had a large effect on exacerbating depression-like behaviors, but there was high heterogeneity [-1.09 (−1.57, −0.62); I2 = 90.3%; P < 0.05]. Subgroup analysis showed that tail suspension test better reflected the effect of SD in exacerbating depression-like behavior [−3.677 (−4.758, −2.597); I2 = 56.7%; P = 0.001] than forced swimming test [−0.821 (−1.439, −0.203); I2 = 91%; P = 0.009] and sucrose preference test [−1.033 (−1.709, −0.358); I2 = 81.6%; P = 0.003].
This study found that SD worsened depression-like behaviors by tail suspension test. Our results also indicated that the effects of SD on depression in rodents were related to different assessment methods, strains, SD methods and SD types.</description><identifier>ISSN: 0006-8993</identifier><identifier>EISSN: 1872-6240</identifier><identifier>DOI: 10.1016/j.brainres.2022.147841</identifier><identifier>PMID: 35183523</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Animals ; Depression ; Forced swimming test ; Hindlimb Suspension ; Meta-analysis ; Rodentia ; Rodents ; Sleep deprivation ; Sleep Deprivation - complications ; Sucrose preference test ; Swimming ; Tail suspension test</subject><ispartof>Brain research, 2022-05, Vol.1782, p.147841-147841, Article 147841</ispartof><rights>2022 Elsevier B.V.</rights><rights>Copyright © 2022 Elsevier B.V. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c368t-230e2227536bbe6a0863513f499ccf5c4605472050c7938c90e5499a8a6aa6393</citedby><cites>FETCH-LOGICAL-c368t-230e2227536bbe6a0863513f499ccf5c4605472050c7938c90e5499a8a6aa6393</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.brainres.2022.147841$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35183523$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hu, Baiqi</creatorcontrib><creatorcontrib>Liu, Chunyan</creatorcontrib><creatorcontrib>Lv, Tingting</creatorcontrib><creatorcontrib>Luo, Fangyi</creatorcontrib><creatorcontrib>Qian, Chao</creatorcontrib><creatorcontrib>Zhang, Jian</creatorcontrib><creatorcontrib>Ye, Mengfei</creatorcontrib><creatorcontrib>Liu, Zheng</creatorcontrib><title>Meta-analysis of sleep deprivation effects on depression in rodents</title><title>Brain research</title><addtitle>Brain Res</addtitle><description>•We provide an evaluation of the experimental SD effects on depression in rodents.•We explore the heterogeneous factors that may be associated with outcomes (eg. strains, test method).•We found that SD worsened depression-like behaviors by tail suspension test.
To our knowledge, the relationship of sleep deprivation (SD) and depression on the rodents remains unclear. In this article, we performed a meta-analysis to provide a comprehensive evaluation of the experimental effects of SD on rodents and explore the heterogeneous factors that may be associated with outcomes.
PubMed, Embase, the Cochrane Library, and Web of Science were searched for articles before January 5th, 2022. The strains of rodents, SD method, and depression measurement tools were recorded. Standardized mean differences based on Hedge’s g were calculated as measures of the effect size.
In total, 19 studies involving 51 trials were included. The overall data suggested that SD had a large effect on exacerbating depression-like behaviors, but there was high heterogeneity [-1.09 (−1.57, −0.62); I2 = 90.3%; P < 0.05]. Subgroup analysis showed that tail suspension test better reflected the effect of SD in exacerbating depression-like behavior [−3.677 (−4.758, −2.597); I2 = 56.7%; P = 0.001] than forced swimming test [−0.821 (−1.439, −0.203); I2 = 91%; P = 0.009] and sucrose preference test [−1.033 (−1.709, −0.358); I2 = 81.6%; P = 0.003].
This study found that SD worsened depression-like behaviors by tail suspension test. Our results also indicated that the effects of SD on depression in rodents were related to different assessment methods, strains, SD methods and SD types.</description><subject>Animals</subject><subject>Depression</subject><subject>Forced swimming test</subject><subject>Hindlimb Suspension</subject><subject>Meta-analysis</subject><subject>Rodentia</subject><subject>Rodents</subject><subject>Sleep deprivation</subject><subject>Sleep Deprivation - complications</subject><subject>Sucrose preference test</subject><subject>Swimming</subject><subject>Tail suspension test</subject><issn>0006-8993</issn><issn>1872-6240</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMtOwzAQRS0EoqXwC1WWbFL8SBx7B6p4SUVsYG05zkRylTrFk1bi73FJy5bVaGbuPO4hZM7oglEm79aLOlofIuCCU84XrKhUwc7IlKmK55IX9JxMKaUyV1qLCblCXKdUCE0vyUSUTImSiylZvsFgcxts940es77NsAPYZg1so9_bwfchg7YFN6Rm-C0D4qHqQxb7BsKA1-SitR3CzTHOyOfT48fyJV-9P78uH1a5E1INORcUOOdVKWRdg7RUyfSHaAutnWtLV0haFhWnJXWVFsppCmXqWWWltVJoMSO3495t7L92gIPZeHTQdTZAv0PDpWDJuRQySeUodbFHjNCaZGdj47dh1BwAmrU5ATQHgGYEmAbnxxu7egPN39iJWBLcjwJITvceokHnIThofEyUTNP7_278ACveg6g</recordid><startdate>20220501</startdate><enddate>20220501</enddate><creator>Hu, Baiqi</creator><creator>Liu, Chunyan</creator><creator>Lv, Tingting</creator><creator>Luo, Fangyi</creator><creator>Qian, Chao</creator><creator>Zhang, Jian</creator><creator>Ye, Mengfei</creator><creator>Liu, Zheng</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20220501</creationdate><title>Meta-analysis of sleep deprivation effects on depression in rodents</title><author>Hu, Baiqi ; Liu, Chunyan ; Lv, Tingting ; Luo, Fangyi ; Qian, Chao ; Zhang, Jian ; Ye, Mengfei ; Liu, Zheng</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c368t-230e2227536bbe6a0863513f499ccf5c4605472050c7938c90e5499a8a6aa6393</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Animals</topic><topic>Depression</topic><topic>Forced swimming test</topic><topic>Hindlimb Suspension</topic><topic>Meta-analysis</topic><topic>Rodentia</topic><topic>Rodents</topic><topic>Sleep deprivation</topic><topic>Sleep Deprivation - complications</topic><topic>Sucrose preference test</topic><topic>Swimming</topic><topic>Tail suspension test</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hu, Baiqi</creatorcontrib><creatorcontrib>Liu, Chunyan</creatorcontrib><creatorcontrib>Lv, Tingting</creatorcontrib><creatorcontrib>Luo, Fangyi</creatorcontrib><creatorcontrib>Qian, Chao</creatorcontrib><creatorcontrib>Zhang, Jian</creatorcontrib><creatorcontrib>Ye, Mengfei</creatorcontrib><creatorcontrib>Liu, Zheng</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Brain research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hu, Baiqi</au><au>Liu, Chunyan</au><au>Lv, Tingting</au><au>Luo, Fangyi</au><au>Qian, Chao</au><au>Zhang, Jian</au><au>Ye, Mengfei</au><au>Liu, Zheng</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Meta-analysis of sleep deprivation effects on depression in rodents</atitle><jtitle>Brain research</jtitle><addtitle>Brain Res</addtitle><date>2022-05-01</date><risdate>2022</risdate><volume>1782</volume><spage>147841</spage><epage>147841</epage><pages>147841-147841</pages><artnum>147841</artnum><issn>0006-8993</issn><eissn>1872-6240</eissn><abstract>•We provide an evaluation of the experimental SD effects on depression in rodents.•We explore the heterogeneous factors that may be associated with outcomes (eg. strains, test method).•We found that SD worsened depression-like behaviors by tail suspension test.
To our knowledge, the relationship of sleep deprivation (SD) and depression on the rodents remains unclear. In this article, we performed a meta-analysis to provide a comprehensive evaluation of the experimental effects of SD on rodents and explore the heterogeneous factors that may be associated with outcomes.
PubMed, Embase, the Cochrane Library, and Web of Science were searched for articles before January 5th, 2022. The strains of rodents, SD method, and depression measurement tools were recorded. Standardized mean differences based on Hedge’s g were calculated as measures of the effect size.
In total, 19 studies involving 51 trials were included. The overall data suggested that SD had a large effect on exacerbating depression-like behaviors, but there was high heterogeneity [-1.09 (−1.57, −0.62); I2 = 90.3%; P < 0.05]. Subgroup analysis showed that tail suspension test better reflected the effect of SD in exacerbating depression-like behavior [−3.677 (−4.758, −2.597); I2 = 56.7%; P = 0.001] than forced swimming test [−0.821 (−1.439, −0.203); I2 = 91%; P = 0.009] and sucrose preference test [−1.033 (−1.709, −0.358); I2 = 81.6%; P = 0.003].
This study found that SD worsened depression-like behaviors by tail suspension test. Our results also indicated that the effects of SD on depression in rodents were related to different assessment methods, strains, SD methods and SD types.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>35183523</pmid><doi>10.1016/j.brainres.2022.147841</doi><tpages>1</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0006-8993 |
| ispartof | Brain research, 2022-05, Vol.1782, p.147841-147841, Article 147841 |
| issn | 0006-8993 1872-6240 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2631624636 |
| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Animals Depression Forced swimming test Hindlimb Suspension Meta-analysis Rodentia Rodents Sleep deprivation Sleep Deprivation - complications Sucrose preference test Swimming Tail suspension test |
| title | Meta-analysis of sleep deprivation effects on depression in rodents |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-20T08%3A57%3A14IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Meta-analysis%20of%20sleep%20deprivation%20effects%20on%20depression%20in%20rodents&rft.jtitle=Brain%20research&rft.au=Hu,%20Baiqi&rft.date=2022-05-01&rft.volume=1782&rft.spage=147841&rft.epage=147841&rft.pages=147841-147841&rft.artnum=147841&rft.issn=0006-8993&rft.eissn=1872-6240&rft_id=info:doi/10.1016/j.brainres.2022.147841&rft_dat=%3Cproquest_cross%3E2631624636%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2631624636&rft_id=info:pmid/35183523&rft_els_id=S0006899322000658&rfr_iscdi=true |