The impact of an exercise intervention on frailty levels in hospitalised older adults: secondary analysis of a randomised controlled trial
Abstract Background physical activity reduces frailty in community-dwelling older adults. How exercise influences frailty in hospitalised older adults requires additional investigation. Objectives (i) to examine the impact of an exercise intervention on frailty in older adults admitted to an acute c...
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| Veröffentlicht in: | Age and ageing 2022-02, Vol.51 (2) |
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| creator | Pérez-Zepeda, Mario Ulises Martínez-Velilla, Nicolás Kehler, Dustin Scott Izquierdo, Mikel Rockwood, Kenneth Theou, Olga |
| description | Abstract
Background
physical activity reduces frailty in community-dwelling older adults. How exercise influences frailty in hospitalised older adults requires additional investigation.
Objectives
(i) to examine the impact of an exercise intervention on frailty in older adults admitted to an acute care ward, and (ii) to determine the impact of baseline frailty on the effectiveness of this intervention.
Setting/participants
this is a secondary analysis of a randomised controlled clinical trial that tested an intensive exercise intervention in ≥75-year-old adults admitted to an acute care ward.
Methods
the intervention included two daily sessions of moderate-intensity exercises (control received usual care). A 63-item Frailty Index (FI) was constructed, and three groups were formed: |
| doi_str_mv | 10.1093/ageing/afac028 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2630922762</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><oup_id>10.1093/ageing/afac028</oup_id><sourcerecordid>2630922762</sourcerecordid><originalsourceid>FETCH-LOGICAL-c397t-2a674d4dacd1c4d35228758b8497de05e169dcc4e0cfb50ac6583aa83e3c251a3</originalsourceid><addsrcrecordid>eNqFkU1v1DAQhi0EokvhyhFZ4gKHtP6IE4cbqviSKnEp52jWnrSuvHGwnYr9C_xqht2FAxckS_aMn3k1r17GXkpxIcWgL-EWw3x7CRM4oewjtpFtZxtldfuYbYQQqhG9Gs7Ys1LuqZRGqqfsTBtpCe837OfNHfKwW8BVniYOM8cfmF0o1J0r5geca0gzpzNlCLHuecQHjIW--V0qS6gQifY8RY-Zg19jLe94QZdmD3lPkhD3JZSDPM8w-7Q7DBBQc4qRnjUHiM_ZkwliwRen-5x9-_jh5upzc_3105er99eN00NfGwVd3_rWg_PStV4bRUaM3dp26D0Kg7IbvHMtCjdtjQDXGasBrEbtlJGgz9mbo-6S0_cVSx1pH4cxwoxpLaPqtBiU6jtF6Ot_0Pu0ZjJ0oKwxre0Hoi6OlMuplIzTuOSwI--jFOPvlMZjSuMpJRp4dZJdtzv0f_E_sRDw9gikdfmf2C_wk6B0</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2638554879</pqid></control><display><type>article</type><title>The impact of an exercise intervention on frailty levels in hospitalised older adults: secondary analysis of a randomised controlled trial</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Applied Social Sciences Index & Abstracts (ASSIA)</source><source>Oxford University Press Journals All Titles (1996-Current)</source><source>Alma/SFX Local Collection</source><creator>Pérez-Zepeda, Mario Ulises ; Martínez-Velilla, Nicolás ; Kehler, Dustin Scott ; Izquierdo, Mikel ; Rockwood, Kenneth ; Theou, Olga</creator><creatorcontrib>Pérez-Zepeda, Mario Ulises ; Martínez-Velilla, Nicolás ; Kehler, Dustin Scott ; Izquierdo, Mikel ; Rockwood, Kenneth ; Theou, Olga</creatorcontrib><description>Abstract
Background
physical activity reduces frailty in community-dwelling older adults. How exercise influences frailty in hospitalised older adults requires additional investigation.
Objectives
(i) to examine the impact of an exercise intervention on frailty in older adults admitted to an acute care ward, and (ii) to determine the impact of baseline frailty on the effectiveness of this intervention.
Setting/participants
this is a secondary analysis of a randomised controlled clinical trial that tested an intensive exercise intervention in ≥75-year-old adults admitted to an acute care ward.
Methods
the intervention included two daily sessions of moderate-intensity exercises (control received usual care). A 63-item Frailty Index (FI) was constructed, and three groups were formed: <0.2, 0.2–0.29 and ≥0.3. Other outcomes included Short Physical Performance Battery (SPPB) and Barthel Index (BI).
Results
a total of 323 individuals were included. The mean age was 87.1 years (± 4.8 standard deviation [SD]) and 56.3% were females. The intervention group improved FI from 0.26 (± 0.10 SD) to 0.20 (± 0.10 SD), whereas the control group FI worsened from 0.25 (± 0.1 SD) to 0.27 (± 0.10 SD). After stratifying by baseline FI, SPPB and depression improved in the intervention group across all levels of frailty; FI, BI and quality of life only improved in individuals with a baseline FI ≥ 0.2.
Conclusions
frailty improves with an intensive individualised exercise intervention, especially in those with high baseline levels of frailty. In addition, frailty is a useful outcome when examining the impact of an intervention of hospitalised older adults.</description><identifier>ISSN: 0002-0729</identifier><identifier>EISSN: 1468-2834</identifier><identifier>DOI: 10.1093/ageing/afac028</identifier><identifier>PMID: 35180287</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><subject>Acute services ; Aged ; Aged, 80 and over ; Barthel Index ; Clinical research ; Clinical trials ; Exercise ; Exercise Therapy ; Female ; Frailty ; Frailty - diagnosis ; Frailty - therapy ; Humans ; Independent Living ; Intensive treatment ; Intervention ; Older people ; Physical activity ; Physical fitness ; Physical training ; Quality of Life</subject><ispartof>Age and ageing, 2022-02, Vol.51 (2)</ispartof><rights>The Author(s) 2022. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For permissions, please email: journals.permissions@oup.com. 2022</rights><rights>The Author(s) 2022. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For permissions, please email: journals.permissions@oup.com.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c397t-2a674d4dacd1c4d35228758b8497de05e169dcc4e0cfb50ac6583aa83e3c251a3</citedby><cites>FETCH-LOGICAL-c397t-2a674d4dacd1c4d35228758b8497de05e169dcc4e0cfb50ac6583aa83e3c251a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,1578,27903,27904,30978</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35180287$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pérez-Zepeda, Mario Ulises</creatorcontrib><creatorcontrib>Martínez-Velilla, Nicolás</creatorcontrib><creatorcontrib>Kehler, Dustin Scott</creatorcontrib><creatorcontrib>Izquierdo, Mikel</creatorcontrib><creatorcontrib>Rockwood, Kenneth</creatorcontrib><creatorcontrib>Theou, Olga</creatorcontrib><title>The impact of an exercise intervention on frailty levels in hospitalised older adults: secondary analysis of a randomised controlled trial</title><title>Age and ageing</title><addtitle>Age Ageing</addtitle><description>Abstract
Background
physical activity reduces frailty in community-dwelling older adults. How exercise influences frailty in hospitalised older adults requires additional investigation.
Objectives
(i) to examine the impact of an exercise intervention on frailty in older adults admitted to an acute care ward, and (ii) to determine the impact of baseline frailty on the effectiveness of this intervention.
Setting/participants
this is a secondary analysis of a randomised controlled clinical trial that tested an intensive exercise intervention in ≥75-year-old adults admitted to an acute care ward.
Methods
the intervention included two daily sessions of moderate-intensity exercises (control received usual care). A 63-item Frailty Index (FI) was constructed, and three groups were formed: <0.2, 0.2–0.29 and ≥0.3. Other outcomes included Short Physical Performance Battery (SPPB) and Barthel Index (BI).
Results
a total of 323 individuals were included. The mean age was 87.1 years (± 4.8 standard deviation [SD]) and 56.3% were females. The intervention group improved FI from 0.26 (± 0.10 SD) to 0.20 (± 0.10 SD), whereas the control group FI worsened from 0.25 (± 0.1 SD) to 0.27 (± 0.10 SD). After stratifying by baseline FI, SPPB and depression improved in the intervention group across all levels of frailty; FI, BI and quality of life only improved in individuals with a baseline FI ≥ 0.2.
Conclusions
frailty improves with an intensive individualised exercise intervention, especially in those with high baseline levels of frailty. In addition, frailty is a useful outcome when examining the impact of an intervention of hospitalised older adults.</description><subject>Acute services</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Barthel Index</subject><subject>Clinical research</subject><subject>Clinical trials</subject><subject>Exercise</subject><subject>Exercise Therapy</subject><subject>Female</subject><subject>Frailty</subject><subject>Frailty - diagnosis</subject><subject>Frailty - therapy</subject><subject>Humans</subject><subject>Independent Living</subject><subject>Intensive treatment</subject><subject>Intervention</subject><subject>Older people</subject><subject>Physical activity</subject><subject>Physical fitness</subject><subject>Physical training</subject><subject>Quality of Life</subject><issn>0002-0729</issn><issn>1468-2834</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>7QJ</sourceid><recordid>eNqFkU1v1DAQhi0EokvhyhFZ4gKHtP6IE4cbqviSKnEp52jWnrSuvHGwnYr9C_xqht2FAxckS_aMn3k1r17GXkpxIcWgL-EWw3x7CRM4oewjtpFtZxtldfuYbYQQqhG9Gs7Ys1LuqZRGqqfsTBtpCe837OfNHfKwW8BVniYOM8cfmF0o1J0r5geca0gzpzNlCLHuecQHjIW--V0qS6gQifY8RY-Zg19jLe94QZdmD3lPkhD3JZSDPM8w-7Q7DBBQc4qRnjUHiM_ZkwliwRen-5x9-_jh5upzc_3105er99eN00NfGwVd3_rWg_PStV4bRUaM3dp26D0Kg7IbvHMtCjdtjQDXGasBrEbtlJGgz9mbo-6S0_cVSx1pH4cxwoxpLaPqtBiU6jtF6Ot_0Pu0ZjJ0oKwxre0Hoi6OlMuplIzTuOSwI--jFOPvlMZjSuMpJRp4dZJdtzv0f_E_sRDw9gikdfmf2C_wk6B0</recordid><startdate>20220202</startdate><enddate>20220202</enddate><creator>Pérez-Zepeda, Mario Ulises</creator><creator>Martínez-Velilla, Nicolás</creator><creator>Kehler, Dustin Scott</creator><creator>Izquierdo, Mikel</creator><creator>Rockwood, Kenneth</creator><creator>Theou, Olga</creator><general>Oxford University Press</general><general>Oxford Publishing Limited (England)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QJ</scope><scope>7T5</scope><scope>7TK</scope><scope>7U9</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>20220202</creationdate><title>The impact of an exercise intervention on frailty levels in hospitalised older adults: secondary analysis of a randomised controlled trial</title><author>Pérez-Zepeda, Mario Ulises ; Martínez-Velilla, Nicolás ; Kehler, Dustin Scott ; Izquierdo, Mikel ; Rockwood, Kenneth ; Theou, Olga</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c397t-2a674d4dacd1c4d35228758b8497de05e169dcc4e0cfb50ac6583aa83e3c251a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Acute services</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Barthel Index</topic><topic>Clinical research</topic><topic>Clinical trials</topic><topic>Exercise</topic><topic>Exercise Therapy</topic><topic>Female</topic><topic>Frailty</topic><topic>Frailty - diagnosis</topic><topic>Frailty - therapy</topic><topic>Humans</topic><topic>Independent Living</topic><topic>Intensive treatment</topic><topic>Intervention</topic><topic>Older people</topic><topic>Physical activity</topic><topic>Physical fitness</topic><topic>Physical training</topic><topic>Quality of Life</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pérez-Zepeda, Mario Ulises</creatorcontrib><creatorcontrib>Martínez-Velilla, Nicolás</creatorcontrib><creatorcontrib>Kehler, Dustin Scott</creatorcontrib><creatorcontrib>Izquierdo, Mikel</creatorcontrib><creatorcontrib>Rockwood, Kenneth</creatorcontrib><creatorcontrib>Theou, Olga</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Applied Social Sciences Index & Abstracts (ASSIA)</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Age and ageing</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pérez-Zepeda, Mario Ulises</au><au>Martínez-Velilla, Nicolás</au><au>Kehler, Dustin Scott</au><au>Izquierdo, Mikel</au><au>Rockwood, Kenneth</au><au>Theou, Olga</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The impact of an exercise intervention on frailty levels in hospitalised older adults: secondary analysis of a randomised controlled trial</atitle><jtitle>Age and ageing</jtitle><addtitle>Age Ageing</addtitle><date>2022-02-02</date><risdate>2022</risdate><volume>51</volume><issue>2</issue><issn>0002-0729</issn><eissn>1468-2834</eissn><abstract>Abstract
Background
physical activity reduces frailty in community-dwelling older adults. How exercise influences frailty in hospitalised older adults requires additional investigation.
Objectives
(i) to examine the impact of an exercise intervention on frailty in older adults admitted to an acute care ward, and (ii) to determine the impact of baseline frailty on the effectiveness of this intervention.
Setting/participants
this is a secondary analysis of a randomised controlled clinical trial that tested an intensive exercise intervention in ≥75-year-old adults admitted to an acute care ward.
Methods
the intervention included two daily sessions of moderate-intensity exercises (control received usual care). A 63-item Frailty Index (FI) was constructed, and three groups were formed: <0.2, 0.2–0.29 and ≥0.3. Other outcomes included Short Physical Performance Battery (SPPB) and Barthel Index (BI).
Results
a total of 323 individuals were included. The mean age was 87.1 years (± 4.8 standard deviation [SD]) and 56.3% were females. The intervention group improved FI from 0.26 (± 0.10 SD) to 0.20 (± 0.10 SD), whereas the control group FI worsened from 0.25 (± 0.1 SD) to 0.27 (± 0.10 SD). After stratifying by baseline FI, SPPB and depression improved in the intervention group across all levels of frailty; FI, BI and quality of life only improved in individuals with a baseline FI ≥ 0.2.
Conclusions
frailty improves with an intensive individualised exercise intervention, especially in those with high baseline levels of frailty. In addition, frailty is a useful outcome when examining the impact of an intervention of hospitalised older adults.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>35180287</pmid><doi>10.1093/ageing/afac028</doi><oa>free_for_read</oa></addata></record> |
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| subjects | Acute services Aged Aged, 80 and over Barthel Index Clinical research Clinical trials Exercise Exercise Therapy Female Frailty Frailty - diagnosis Frailty - therapy Humans Independent Living Intensive treatment Intervention Older people Physical activity Physical fitness Physical training Quality of Life |
| title | The impact of an exercise intervention on frailty levels in hospitalised older adults: secondary analysis of a randomised controlled trial |
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