Regulation of PTEN and ovarian cancer progression by an E3 ubiquitin ligase RBCK1

Ovarian cancer is one of the most lethal gynecologic malignancies worldwide, with the 5-year survival is less than 50%. Although some clinical achievements have been achieved, the overall survival rate has remained unchanged over the past 20 years. Therefore, it is necessary and urgent to develop th...

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Veröffentlicht in:	Human cell : official journal of Human Cell Research Society 2022-05, Vol.35 (3), p.896-908
Hauptverfasser:	Wang, Guanghui, Zhuang, Zi, Shen, Siyuan, Yang, Fan, Jiang, Zhiyuan, Liu, Ziping, Wang, Tianshi, Hua, Lei
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Biomedical and Life Sciences Cell Biology Cell Line, Tumor Cell migration Cell proliferation Cell Proliferation - genetics Female Gynecology Humans Life Sciences Medical prognosis Oncology Ovarian cancer Ovarian Neoplasms - genetics Ovarian Neoplasms - therapy Patients PTEN Phosphohydrolase - genetics PTEN Phosphohydrolase - metabolism PTEN protein Reproductive Medicine Research Article Stem Cells Surgery Therapeutic targets Transcription Factors - genetics Ubiquitin Ubiquitin-protein ligase Ubiquitin-Protein Ligases - genetics Ubiquitin-Protein Ligases - metabolism Ubiquitination
Online-Zugang:	Volltext
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