Novel boron‐containing compound, halogenated boroxine, induces selective cytotoxicity through apoptosis triggering in UT‐7 leukemia

Apoptosis induction is a promising approach in targeting tumor cells. As halogenated boroxine (HB) shows antitumor activity, but its mechanism of action in hematological tumors remains unclear, in this study, we aimed to analyze apoptosis triggering in normal and UT‐7 leukemia cells by HB. Methods f...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of biochemical and molecular toxicology 2022-05, Vol.36 (5), p.e23005-n/a
Hauptverfasser:	Hadzic, Maida, Pojskic, Lejla, Lojo‐Kadric, Naida, Haveric, Anja, Ramic, Jasmin, Galic, Borivoj, Haveric, Sanin
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticancer properties Antitumor activity antitumor effect Apoptosis BCCs Boron Cell Line, Tumor Cell viability Cytotoxicity Functional analysis Gene expression Genes Humans Leukemia Leukemia - drug therapy Leukemia - pathology NF-kappa B - metabolism Proto-Oncogene Proteins c-bcl-2 - genetics selectivity action Signal transduction Toxicity Tumor cells Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!