Distinct pathologic feature of myeloid neoplasm with t(v;11p15); NUP98 rearrangement

Chromosome rearrangements involving NUP98 at 11p15 are rare but recurring abnormalities in acute myeloid leukemia (AML). Here we described 12 cases of myeloid neoplasms with t(v; 11p15); NUP98 rearrangement and characterized their pathologic features. Our patient cohort included 10 adults and 2 chil...

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Veröffentlicht in:	Human pathology 2022-05, Vol.123, p.11-19
Hauptverfasser:	Lauw, Marietya I.S., Qi, Zhongxia, Eversmeyer, Lauren, Prakash, Sonam, Wen, Kwun Wah, Yu, Jingwei, Monaghan, Sara A., Aggarwal, Nidhi, Wang, Linlin
Format:	Artikel
Sprache:	eng
Schlagworte:	Bone marrow Chemotherapy Chromosome Aberrations Chromosomes Flow cytometry Genes Humans In Situ Hybridization, Fluorescence Laboratories Leukemia Leukemia, Myeloid, Acute - genetics Lymphoma Middle Aged Morphology Myelodysplastic syndromes Myeloid neoplasm Myeloproliferative Disorders - genetics Nuclear Pore Complex Proteins - genetics NUP98 FISH NUP98 rearrangement Patients Pediatrics Remission (Medicine) t(v 11p15) Translocation, Genetic Tumors
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