IL-25 participates in keratinocyte-driven dermal matrix turnover and is reduced in Systemic Sclerosis epidermis

Evidence shows that dysfunctional SSc keratinocytes contribute to fibrosis by altering dermal homeostasis. Whether interleukin-25 (IL-25), an IL-17 family member regulating many epidermal functions, takes part in skin fibrosis is unknown. Here we address the role of IL-25 in skin fibrosis. The expre...

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Veröffentlicht in:Rheumatology (Oxford, England) England), 2022-11, Vol.61 (11), p.4558-4569
Hauptverfasser: Russo, Barbara, Borowczyk, Julia, Cacialli, Pietro, Moguelet, Philippe, Truchetet, Marie-Elise, Modarressi, Ali, Brembilla, Nicolò C, Bertrand, Julien, Boehncke, Wolf-Henning, Chizzolini, Carlo
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Sprache:eng
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