Serum albumin at 1 year after peritoneal dialysis predicts long-term outcomes on continuous ambulatory peritoneal dialysis
Hypoalbuminemia at baseline is a powerful predictor of long-term outcomes in peritoneal dialysis patients. However, the levels of serum albumin are dynamically changed during PD. The present study investigated whether the improvement of hypoalbuminemia during PD can affect the patients' outcome...
Gespeichert in:
| Veröffentlicht in: | Renal failure 2022-12, Vol.44 (1), p.252-257 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 257 |
|---|---|
| container_issue | 1 |
| container_start_page | 252 |
| container_title | Renal failure |
| container_volume | 44 |
| creator | Jin, Li Wang, Xiaopei Ma, Ying Zheng, Jie Lu, Wanhong Xie, Liyi Lv, Jing |
| description | Hypoalbuminemia at baseline is a powerful predictor of long-term outcomes in peritoneal dialysis patients. However, the levels of serum albumin are dynamically changed during PD. The present study investigated whether the improvement of hypoalbuminemia during PD can affect the patients' outcomes.
436 consecutive incidents continuous ambulatory peritoneal dialysis patients were involved in this study. Demographic, hematologic, biochemical, and dialysis-related data at baseline as well as 1 year after PD were collected. All patients were followed for at least 1 year for mortality.
Among the 436 patients, the mean age was 48.44 ± 14.98 years, with 58.26% males and 18.12% prevalence of diabetes. The mean follow-up time was 48.25 ± 24.05 months. During the follow-up period, a total of 68 patients died. Serum albumin was 34.35 ± 5.65 g/L at baseline, which increased to 37.39 ± 5.05 g/L at 1 year after PD. Multivariate linear regression analysis showed that sex, age, BMI, diabetic nephropathy, as well as albumin at baseline were independently associated with albumin at 1 year. Every 1 year of age rise would result in a 3.9% increase in the risk of mortality (HR = 1.039, 95%CI 1.016-1.061, p = 0.001). Every 1 g/L increase in albumin at 1 year after PD confers an 8.7% decrease in the risk of mortality (HR = 0.913, 95%CI 0.856-0.973, p = 0.005).
The level of serum albumin was increased in the first year of PD. Serum albumin after 1 year of PD predicted mortality in peritoneal dialysis. |
| doi_str_mv | 10.1080/0886022X.2022.2033264 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_infor</sourceid><recordid>TN_cdi_proquest_miscellaneous_2629059492</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><doaj_id>oai_doaj_org_article_a7ff86ba082e4b7f9835484b75ca6544</doaj_id><sourcerecordid>2780608747</sourcerecordid><originalsourceid>FETCH-LOGICAL-c562t-58f6e3ce706a2645b76b869c18cd538839ca08392df15590da20c6bce88dc2e53</originalsourceid><addsrcrecordid>eNp9kkFvFCEYhonR2LX6EzQkXrxMBWZgmIuxaao2aeJBTbyRbxhY2TCwAqNZf31Zd9tYY7x8EHh44CMvQs8pOaNEktdESkEY-3rGaq2lbZnoHqAV5Yw3gnTDQ7TaM80eOkFPct4QQrns2WN00nIqBJVihX59MmmZMfhxmV3AUDDFOwMJgy0m4a1JrsRgwOPJgd9ll_E2mcnpkrGPYd1UasZxKTrOJuMYsI6huLDEJWOYx8VDiWn3L9FT9MiCz-bZcTxFX95dfr740Fx_fH91cX7daC5Yabi0wrTa9ERAbZGPvRilGDSVeuKtlO2ggdTKJks5H8gEjGgxaiPlpJnh7Sm6OninCBu1TW6GtFMRnPq9ENNaQSpOe6Ogt1aKsfqY6cbeDrLlnawzrkHwrquuNwfXdhlnM2kTSgJ_T3p_J7hvah1_KCm5oIRWwaujIMXvi8lFzS5r4z0EU79MMcEGwoduYBV9-Re6iUsK9asU6yURRPZdXyl-oHSKOSdj7x5DidonRd0mRe2Too5Jqede_NnJ3anbaFTg7QFwwcY0w8-Y_KQK7HxMNkHQLqv2_3fcAI1W0Cc</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2780608747</pqid></control><display><type>article</type><title>Serum albumin at 1 year after peritoneal dialysis predicts long-term outcomes on continuous ambulatory peritoneal dialysis</title><source>Taylor & Francis Open Access</source><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Jin, Li ; Wang, Xiaopei ; Ma, Ying ; Zheng, Jie ; Lu, Wanhong ; Xie, Liyi ; Lv, Jing</creator><creatorcontrib>Jin, Li ; Wang, Xiaopei ; Ma, Ying ; Zheng, Jie ; Lu, Wanhong ; Xie, Liyi ; Lv, Jing</creatorcontrib><description>Hypoalbuminemia at baseline is a powerful predictor of long-term outcomes in peritoneal dialysis patients. However, the levels of serum albumin are dynamically changed during PD. The present study investigated whether the improvement of hypoalbuminemia during PD can affect the patients' outcomes.
436 consecutive incidents continuous ambulatory peritoneal dialysis patients were involved in this study. Demographic, hematologic, biochemical, and dialysis-related data at baseline as well as 1 year after PD were collected. All patients were followed for at least 1 year for mortality.
Among the 436 patients, the mean age was 48.44 ± 14.98 years, with 58.26% males and 18.12% prevalence of diabetes. The mean follow-up time was 48.25 ± 24.05 months. During the follow-up period, a total of 68 patients died. Serum albumin was 34.35 ± 5.65 g/L at baseline, which increased to 37.39 ± 5.05 g/L at 1 year after PD. Multivariate linear regression analysis showed that sex, age, BMI, diabetic nephropathy, as well as albumin at baseline were independently associated with albumin at 1 year. Every 1 year of age rise would result in a 3.9% increase in the risk of mortality (HR = 1.039, 95%CI 1.016-1.061, p = 0.001). Every 1 g/L increase in albumin at 1 year after PD confers an 8.7% decrease in the risk of mortality (HR = 0.913, 95%CI 0.856-0.973, p = 0.005).
The level of serum albumin was increased in the first year of PD. Serum albumin after 1 year of PD predicted mortality in peritoneal dialysis.</description><identifier>ISSN: 0886-022X</identifier><identifier>EISSN: 1525-6049</identifier><identifier>DOI: 10.1080/0886022X.2022.2033264</identifier><identifier>PMID: 35166186</identifier><language>eng</language><publisher>England: Taylor & Francis</publisher><subject>Adult ; Age ; Albumin ; Clinical Study ; Diabetes mellitus ; Female ; Hemodialysis ; Humans ; Hypoalbuminemia - epidemiology ; Linear Models ; Male ; Middle Aged ; Mortality ; Multivariate Analysis ; Nephropathy ; Peritoneal dialysis ; Peritoneal Dialysis, Continuous Ambulatory - mortality ; Peritoneum ; serum albumin ; Serum Albumin - analysis ; Time Factors</subject><ispartof>Renal failure, 2022-12, Vol.44 (1), p.252-257</ispartof><rights>2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. 2022</rights><rights>2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. This work is licensed under the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. 2022 The Author(s)</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c562t-58f6e3ce706a2645b76b869c18cd538839ca08392df15590da20c6bce88dc2e53</citedby><cites>FETCH-LOGICAL-c562t-58f6e3ce706a2645b76b869c18cd538839ca08392df15590da20c6bce88dc2e53</cites><orcidid>0000-0003-3601-2604</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856101/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856101/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,724,777,781,861,882,2096,27483,27905,27906,53772,53774,59122,59123</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35166186$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jin, Li</creatorcontrib><creatorcontrib>Wang, Xiaopei</creatorcontrib><creatorcontrib>Ma, Ying</creatorcontrib><creatorcontrib>Zheng, Jie</creatorcontrib><creatorcontrib>Lu, Wanhong</creatorcontrib><creatorcontrib>Xie, Liyi</creatorcontrib><creatorcontrib>Lv, Jing</creatorcontrib><title>Serum albumin at 1 year after peritoneal dialysis predicts long-term outcomes on continuous ambulatory peritoneal dialysis</title><title>Renal failure</title><addtitle>Ren Fail</addtitle><description>Hypoalbuminemia at baseline is a powerful predictor of long-term outcomes in peritoneal dialysis patients. However, the levels of serum albumin are dynamically changed during PD. The present study investigated whether the improvement of hypoalbuminemia during PD can affect the patients' outcomes.
436 consecutive incidents continuous ambulatory peritoneal dialysis patients were involved in this study. Demographic, hematologic, biochemical, and dialysis-related data at baseline as well as 1 year after PD were collected. All patients were followed for at least 1 year for mortality.
Among the 436 patients, the mean age was 48.44 ± 14.98 years, with 58.26% males and 18.12% prevalence of diabetes. The mean follow-up time was 48.25 ± 24.05 months. During the follow-up period, a total of 68 patients died. Serum albumin was 34.35 ± 5.65 g/L at baseline, which increased to 37.39 ± 5.05 g/L at 1 year after PD. Multivariate linear regression analysis showed that sex, age, BMI, diabetic nephropathy, as well as albumin at baseline were independently associated with albumin at 1 year. Every 1 year of age rise would result in a 3.9% increase in the risk of mortality (HR = 1.039, 95%CI 1.016-1.061, p = 0.001). Every 1 g/L increase in albumin at 1 year after PD confers an 8.7% decrease in the risk of mortality (HR = 0.913, 95%CI 0.856-0.973, p = 0.005).
The level of serum albumin was increased in the first year of PD. Serum albumin after 1 year of PD predicted mortality in peritoneal dialysis.</description><subject>Adult</subject><subject>Age</subject><subject>Albumin</subject><subject>Clinical Study</subject><subject>Diabetes mellitus</subject><subject>Female</subject><subject>Hemodialysis</subject><subject>Humans</subject><subject>Hypoalbuminemia - epidemiology</subject><subject>Linear Models</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Multivariate Analysis</subject><subject>Nephropathy</subject><subject>Peritoneal dialysis</subject><subject>Peritoneal Dialysis, Continuous Ambulatory - mortality</subject><subject>Peritoneum</subject><subject>serum albumin</subject><subject>Serum Albumin - analysis</subject><subject>Time Factors</subject><issn>0886-022X</issn><issn>1525-6049</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>0YH</sourceid><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><sourceid>DOA</sourceid><recordid>eNp9kkFvFCEYhonR2LX6EzQkXrxMBWZgmIuxaao2aeJBTbyRbxhY2TCwAqNZf31Zd9tYY7x8EHh44CMvQs8pOaNEktdESkEY-3rGaq2lbZnoHqAV5Yw3gnTDQ7TaM80eOkFPct4QQrns2WN00nIqBJVihX59MmmZMfhxmV3AUDDFOwMJgy0m4a1JrsRgwOPJgd9ll_E2mcnpkrGPYd1UasZxKTrOJuMYsI6huLDEJWOYx8VDiWn3L9FT9MiCz-bZcTxFX95dfr740Fx_fH91cX7daC5Yabi0wrTa9ERAbZGPvRilGDSVeuKtlO2ggdTKJks5H8gEjGgxaiPlpJnh7Sm6OninCBu1TW6GtFMRnPq9ENNaQSpOe6Ogt1aKsfqY6cbeDrLlnawzrkHwrquuNwfXdhlnM2kTSgJ_T3p_J7hvah1_KCm5oIRWwaujIMXvi8lFzS5r4z0EU79MMcEGwoduYBV9-Re6iUsK9asU6yURRPZdXyl-oHSKOSdj7x5DidonRd0mRe2Too5Jqede_NnJ3anbaFTg7QFwwcY0w8-Y_KQK7HxMNkHQLqv2_3fcAI1W0Cc</recordid><startdate>202212</startdate><enddate>202212</enddate><creator>Jin, Li</creator><creator>Wang, Xiaopei</creator><creator>Ma, Ying</creator><creator>Zheng, Jie</creator><creator>Lu, Wanhong</creator><creator>Xie, Liyi</creator><creator>Lv, Jing</creator><general>Taylor & Francis</general><general>Taylor & Francis Ltd</general><general>Taylor & Francis Group</general><scope>0YH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7T5</scope><scope>7XB</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0003-3601-2604</orcidid></search><sort><creationdate>202212</creationdate><title>Serum albumin at 1 year after peritoneal dialysis predicts long-term outcomes on continuous ambulatory peritoneal dialysis</title><author>Jin, Li ; Wang, Xiaopei ; Ma, Ying ; Zheng, Jie ; Lu, Wanhong ; Xie, Liyi ; Lv, Jing</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c562t-58f6e3ce706a2645b76b869c18cd538839ca08392df15590da20c6bce88dc2e53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Adult</topic><topic>Age</topic><topic>Albumin</topic><topic>Clinical Study</topic><topic>Diabetes mellitus</topic><topic>Female</topic><topic>Hemodialysis</topic><topic>Humans</topic><topic>Hypoalbuminemia - epidemiology</topic><topic>Linear Models</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Mortality</topic><topic>Multivariate Analysis</topic><topic>Nephropathy</topic><topic>Peritoneal dialysis</topic><topic>Peritoneal Dialysis, Continuous Ambulatory - mortality</topic><topic>Peritoneum</topic><topic>serum albumin</topic><topic>Serum Albumin - analysis</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jin, Li</creatorcontrib><creatorcontrib>Wang, Xiaopei</creatorcontrib><creatorcontrib>Ma, Ying</creatorcontrib><creatorcontrib>Zheng, Jie</creatorcontrib><creatorcontrib>Lu, Wanhong</creatorcontrib><creatorcontrib>Xie, Liyi</creatorcontrib><creatorcontrib>Lv, Jing</creatorcontrib><collection>Taylor & Francis Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Immunology Abstracts</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Renal failure</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jin, Li</au><au>Wang, Xiaopei</au><au>Ma, Ying</au><au>Zheng, Jie</au><au>Lu, Wanhong</au><au>Xie, Liyi</au><au>Lv, Jing</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Serum albumin at 1 year after peritoneal dialysis predicts long-term outcomes on continuous ambulatory peritoneal dialysis</atitle><jtitle>Renal failure</jtitle><addtitle>Ren Fail</addtitle><date>2022-12</date><risdate>2022</risdate><volume>44</volume><issue>1</issue><spage>252</spage><epage>257</epage><pages>252-257</pages><issn>0886-022X</issn><eissn>1525-6049</eissn><abstract>Hypoalbuminemia at baseline is a powerful predictor of long-term outcomes in peritoneal dialysis patients. However, the levels of serum albumin are dynamically changed during PD. The present study investigated whether the improvement of hypoalbuminemia during PD can affect the patients' outcomes.
436 consecutive incidents continuous ambulatory peritoneal dialysis patients were involved in this study. Demographic, hematologic, biochemical, and dialysis-related data at baseline as well as 1 year after PD were collected. All patients were followed for at least 1 year for mortality.
Among the 436 patients, the mean age was 48.44 ± 14.98 years, with 58.26% males and 18.12% prevalence of diabetes. The mean follow-up time was 48.25 ± 24.05 months. During the follow-up period, a total of 68 patients died. Serum albumin was 34.35 ± 5.65 g/L at baseline, which increased to 37.39 ± 5.05 g/L at 1 year after PD. Multivariate linear regression analysis showed that sex, age, BMI, diabetic nephropathy, as well as albumin at baseline were independently associated with albumin at 1 year. Every 1 year of age rise would result in a 3.9% increase in the risk of mortality (HR = 1.039, 95%CI 1.016-1.061, p = 0.001). Every 1 g/L increase in albumin at 1 year after PD confers an 8.7% decrease in the risk of mortality (HR = 0.913, 95%CI 0.856-0.973, p = 0.005).
The level of serum albumin was increased in the first year of PD. Serum albumin after 1 year of PD predicted mortality in peritoneal dialysis.</abstract><cop>England</cop><pub>Taylor & Francis</pub><pmid>35166186</pmid><doi>10.1080/0886022X.2022.2033264</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0003-3601-2604</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0886-022X |
| ispartof | Renal failure, 2022-12, Vol.44 (1), p.252-257 |
| issn | 0886-022X 1525-6049 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2629059492 |
| source | Taylor & Francis Open Access; MEDLINE; DOAJ Directory of Open Access Journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Adult Age Albumin Clinical Study Diabetes mellitus Female Hemodialysis Humans Hypoalbuminemia - epidemiology Linear Models Male Middle Aged Mortality Multivariate Analysis Nephropathy Peritoneal dialysis Peritoneal Dialysis, Continuous Ambulatory - mortality Peritoneum serum albumin Serum Albumin - analysis Time Factors |
| title | Serum albumin at 1 year after peritoneal dialysis predicts long-term outcomes on continuous ambulatory peritoneal dialysis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-20T13%3A19%3A26IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_infor&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Serum%20albumin%20at%201%20year%20after%20peritoneal%20dialysis%20predicts%20long-term%20outcomes%20on%20continuous%20ambulatory%20peritoneal%20dialysis&rft.jtitle=Renal%20failure&rft.au=Jin,%20Li&rft.date=2022-12&rft.volume=44&rft.issue=1&rft.spage=252&rft.epage=257&rft.pages=252-257&rft.issn=0886-022X&rft.eissn=1525-6049&rft_id=info:doi/10.1080/0886022X.2022.2033264&rft_dat=%3Cproquest_infor%3E2780608747%3C/proquest_infor%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2780608747&rft_id=info:pmid/35166186&rft_doaj_id=oai_doaj_org_article_a7ff86ba082e4b7f9835484b75ca6544&rfr_iscdi=true |