Nano-ultrasonic Contrast Agent for Chemoimmunotherapy of Breast Cancer by Immune Metabolism Reprogramming and Tumor Autophagy

The functional status of innate immune cells is a considerable determinant of effective antitumor immune response. However, the triple-negative breast cancer tumor microenvironment with high lactic acid metabolism and high antioxidant levels limits immune cell survival, differentiation, and function...

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Veröffentlicht in:	ACS nano 2022-02, Vol.16 (2), p.3417-3431
Hauptverfasser:	Yang, Xupeng, Zhao, Meng, Wu, Zhihua, Chen, Chuanrong, Zhang, Yanhua, Wang, Liting, Guo, Qianqian, Wang, Quan, Liang, Shunshun, Hu, Suxian, Duan, Yourong, Sun, Ying
Format:	Artikel
Sprache:	eng
Schlagworte:	Autophagy Cell Line, Tumor Contrast Media - pharmacology Humans Nanoparticles - chemistry Triple Negative Breast Neoplasms - diagnostic imaging Triple Negative Breast Neoplasms - drug therapy Tumor Microenvironment
Online-Zugang:	Volltext
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