Standardization and Maintenance of 3D Canine Hepatic and Intestinal Organoid Cultures for Use in Biomedical Research

Dogs develop complex multifactorial diseases analogous to humans, including inflammatory diseases, metabolic diseases, and cancer. Therefore, they represent relevant large animal models with the translational potential to human medicine. Organoids are 3-dimensional (3D), self-assembled structures de...

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Veröffentlicht in:	Journal of Visualized Experiments 2022-01 (179)
Hauptverfasser:	Gabriel, Vojtech, Zdyrski, Christopher, Sahoo, Dipak K., Dao, Kimberly, Bourgois-Mochel, Agnes, Kopper, Jamie, Zeng, Xi-Lei, Estes, Mary K., Mochel, Jonathan P., Allenspach, Karin
Format:	Artikel
Sprache:	eng
Schlagworte:	adults Animals Biological Specimen Banks Biomedical Research Dogs drugs Intestines Medicine Organoids pathophysiology permeability Reference Standards solubilization toxicology veterinary medicine
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