DNA damage-induced translocation of mitochondrial factor HIGD1A into the nucleus regulates homologous recombination and radio/chemo-sensitivity
HIGD1A is an important mitochondrial protein recently shown to have a novel nuclear localization under severe stress. However, whether this protein is also associated with the DNA damage response has rarely been studied. Here, we reported that DSBs-induced the translocation of mitochondrial HIGD1A t...
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Veröffentlicht in: | Oncogene 2022-03, Vol.41 (13), p.1918-1930 |
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Hauptverfasser: | , , , , , , , , , |
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Sprache: | eng |
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