YAP1 activation promotes epithelial-mesenchymal transition and cell survival of renal cell carcinoma cells under shear stress

Renal cell carcinoma (RCC) is characterized by substantial vasculatures and increased fluid movement in tumor microenvironment, and the fluid shear stress modulates malignance, extravasation and metastatic seeding of tumor cells. However, the precise mechanism remains largely unclear. In this study,...

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Veröffentlicht in:Carcinogenesis (New York) 2022-05, Vol.43 (4), p.301-310
Hauptverfasser: Chen, Xiaopeng, Zhang, Xiaowei, Jiang, Yitong, Zhang, Xuemei, Liu, Min, Wang, Shanna, Liu, Shaoqiong, Liang, Haiyan, Liu, Chunhua
Format: Artikel
Sprache:eng
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