Mdivi-1 alleviates cardiac fibrosis post myocardial infarction at infarcted border zone, possibly via inhibition of Drp1-Activated mitochondrial fission and oxidative stress

Mitochondrial division inhibitor 1(Mdivi-1) has been shown to play a beneficial role in a variety of diseases, mainly by inhibiting Drp1-mediated mitochondrial fission. The effects of Mdivi-1 on cardiac fibrosis at infarcted border zone area and its possible mechanism remain unclear. This study aime...

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Veröffentlicht in:Archives of biochemistry and biophysics 2022-03, Vol.718, p.109147-109147, Article 109147
Hauptverfasser: Ding, Jie, Zhang, Zhihao, Li, Sui, Wang, Wei, Du, Tingyi, Fang, Qin, Wang, Yan, Wang, Dao Wen
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Sprache:eng
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