Attenuation of obesity-induced hyperlipidemia reduces tumor growth

Accumulating evidence suggests that hyperlipidemia is associated with obesity and cancer mortality in humans. We tested the hypotheses that inhibition of microsomal triglyceride transfer protein (MTP) would attenuate obesity-induced hyperlipidemia and reduce tumor growth by treating BCR-ABL B cell t...

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Veröffentlicht in:	Biochimica et biophysica acta. Molecular and cell biology of lipids 2022-04, Vol.1867 (4), p.159124-159124, Article 159124
Hauptverfasser:	Hussain, Aashiq, Lian, Jihong, Watts, Russell, Gutiérrez, Tomás, Nelson, Randal, Goping, Ing Swie, Lehner, Richard
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apolipoprotein B cancer Cholesterol Humans Hyperlipidemias - complications Hyperlipidemias - drug therapy LDL Mice Mice, Obese Microsomal triglyceride transfer protein Neoplasms Obesity - complications Phosphatidylinositol 3-Kinases VLDL
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