Possible Cytoprotection of Low Dose Lipopolysaccharide in Rat Thioacetamide-Induced Liver Lesions, Focusing on the Analyses of Hepatic Macrophages and Autophagy

Lipopolysaccharide (LPS) may influence hepatic macrophages and autophagy. We evaluated the potential participation of macrophages and autophagosomes in thioacetamide (TAA)-induced rat liver injury under pretreatment of a low dose LPS (0.1 mg/kg BW, intraperitoneally; nonhepatotoxic dose). F344 rats...

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Veröffentlicht in:	Toxicologic pathology 2022-04, Vol.50 (3), p.353-365
Hauptverfasser:	Pervin, Munmun, Karim, Mohammad Rabiul, Kuramochi, Mizuki, Izawa, Takeshi, Kuwamura, Mitsuru, Yamate, Jyoji
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autophagy Cytoprotection Lipopolysaccharides - toxicity Liver - pathology Liver Neoplasms - pathology Macrophages - pathology Rats Rats, Inbred F344 Thioacetamide - toxicity
Online-Zugang:	Volltext
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