The Role of Endoplasmic Reticulum and Mitochondria in Maintaining Redox Status and Glycolytic Metabolism in Pluripotent Stem Cells

Pluripotent stem cells (PSCs), including embryonic stem cells and induced pluripotent stem cells (iPSCs), can be applicable for regenerative medicine. They strangely rely on glycolysis metabolism akin to aerobic glycolysis in cancer cells. Upon differentiation, PSCs undergo a metabolic shift from gl...

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Veröffentlicht in:	Stem cell reviews and reports 2022-06, Vol.18 (5), p.1789-1808
Hauptverfasser:	Babaei-Abraki, Shahnaz, Karamali, Fereshteh, Nasr-Esfahani, Mohammad Hossein
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical and Life Sciences Biomedical Engineering and Bioengineering Cell Biology Cell differentiation Cell self-renewal Cell survival Chromatin Embryo cells Endoplasmic reticulum Environmental changes Glycolysis Intermediates Life Sciences Metabolism Mitochondria Organelles Oxidative phosphorylation Phosphorylation Pluripotency Regenerative medicine Regenerative Medicine/Tissue Engineering Senescence Stem Cells Transcriptomes
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