Belzutifan: a novel therapy for von Hippel–Lindau disease

A recent clinical trial reports promising efficacy and safety data for belzutifan in patients with von Hippel–Lindau (VHL) disease–associated renal cell carcinoma. On the basis of these results, belzutifan became the first therapeutic agent to be approved for the systemic treatment of cancer associa...

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Veröffentlicht in:Nature reviews. Nephrology 2022-04, Vol.18 (4), p.205-206
Hauptverfasser: Zhou, Jingcheng, Gong, Kan
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container_title Nature reviews. Nephrology
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creator Zhou, Jingcheng
Gong, Kan
description A recent clinical trial reports promising efficacy and safety data for belzutifan in patients with von Hippel–Lindau (VHL) disease–associated renal cell carcinoma. On the basis of these results, belzutifan became the first therapeutic agent to be approved for the systemic treatment of cancer associated with VHL disease.
doi_str_mv 10.1038/s41581-022-00544-5
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subjects 692/4028/67/1059/602
692/4028/67/589/1588/1351
Antineoplastic Agents - therapeutic use
Cancer therapies
Carcinoma, Renal Cell - pathology
Clinical trials
Female
Humans
Immunotherapy
Kidney cancer
Kidney Neoplasms - pathology
Kinases
Male
Medicine
Medicine & Public Health
Mutation
Nephrology
News & Views
news-and-views
Patients
Proteins
Quality of life
Tumors
Urology
Vascular endothelial growth factor
von Hippel-Lindau Disease - complications
von Hippel-Lindau Disease - drug therapy
title Belzutifan: a novel therapy for von Hippel–Lindau disease
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