The altered lipidome of hepatocellular carcinoma

•Lipidomics profiling and biochemical analyses of human HCCs reveal alterations in glycerophospholipid, sphingolipid, cholesterol and bile acid metabolism.•Glycerophospholipid composition is commonly shifted towards increased MUFA-to-PUFA ratios in HCCs.•Cholesterol esterification is augmented in HC...

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Veröffentlicht in:	Seminars in cancer biology 2022-11, Vol.86 (Pt 3), p.445-456
Hauptverfasser:	Tan, Shawn Lu Wen, Israeli, Erez, Ericksen, Russell E., Chow, Pierce K.H., Han, Weiping
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Carcinogenesis - genetics Carcinoma, Hepatocellular - genetics Cell Transformation, Neoplastic Hepatocellular carcinoma Humans Lipid Lipidomics Liver Neoplasms - etiology Liver Neoplasms - metabolism Metabolism
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