Association of Cardiopulmonary Exercise Capacity and Adipokines in the General Population
Abstract Adipokines and cardiorespiratory fitness (CRF) are associated with the (patho)physiology of cardiometabolic diseases. Whether CRF and adipokines are related is unclear. We investigated associations of CRF with leptin, adiponectin, chemerin, resistin and vaspin. Data from the population-base...
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| Veröffentlicht in: | International journal of sports medicine 2022-06, Vol.43 (7), p.616-624 |
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| container_title | International journal of sports medicine |
| container_volume | 43 |
| creator | Lendeckel, Frederik Zylla, Stephanie Markus, Marcello Ricardo Paulista Ewert, Ralf Gläser, Sven Völzke, Henry Albrecht, Diana Friedrich, Nele Nauck, Matthias Felix, Stephan B Dörr, Marcus Bahls, Martin |
| description | Abstract
Adipokines and cardiorespiratory fitness (CRF) are associated with the
(patho)physiology of cardiometabolic diseases. Whether CRF and adipokines are
related is unclear. We investigated associations of CRF with leptin,
adiponectin, chemerin, resistin and vaspin. Data from the population-based Study
of Health in Pomerania was used (n=1,479; median age 49 years;
51% women). Cardiopulmonary exercise testing was used to measure CRF.
Circulating adipokine concentrations were measured by enzyme-linked
immunosorbent assay. The association between CRF and adipokines was assessed
using multivariable sex-specific quantile regression models. Higher maximum
oxygen uptake was significantly associated with lower leptin
(men:−0.11 ng/ml; 95%-confidence interval
[CI]:−0.18 to−0.03 ng/ml; p |
| doi_str_mv | 10.1055/a-1699-2380 |
| format | Article |
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Adipokines and cardiorespiratory fitness (CRF) are associated with the
(patho)physiology of cardiometabolic diseases. Whether CRF and adipokines are
related is unclear. We investigated associations of CRF with leptin,
adiponectin, chemerin, resistin and vaspin. Data from the population-based Study
of Health in Pomerania was used (n=1,479; median age 49 years;
51% women). Cardiopulmonary exercise testing was used to measure CRF.
Circulating adipokine concentrations were measured by enzyme-linked
immunosorbent assay. The association between CRF and adipokines was assessed
using multivariable sex-specific quantile regression models. Higher maximum
oxygen uptake was significantly associated with lower leptin
(men:−0.11 ng/ml; 95%-confidence interval
[CI]:−0.18 to−0.03 ng/ml; p<0.005;
women:−0.17 ng/ml; 95%-CI:−0.33
to−0.02 ng/ml; p<0.05) and chemerin
(men:−0.26 ng/ml; 95%-CI:−0.52
to−0.01 ng/ml; p<0.05;
women:−0.41 ng/ml; 95%-CI:−0.82
to−0.01 ng/ml; p<0.05) as well as higher
adiponectin concentrations (men: 0.06 µg/ml;
95%-CI: 0.02 to 0.11 µg/ml; p<0.05;
women: 0.03 µg/ml; 95%-CI:−0.05 to
0.10 µg/ml; p=0.48). We found that CRF was
inversely associated with leptin and chemerin in both sexes and positively
associated with adiponectin only in men.</description><identifier>ISSN: 0172-4622</identifier><identifier>EISSN: 1439-3964</identifier><identifier>DOI: 10.1055/a-1699-2380</identifier><identifier>PMID: 35114706</identifier><language>eng</language><publisher>Rüdigerstraße 14, 70469 Stuttgart, Germany: Georg Thieme Verlag KG</publisher><subject>Training & Testing</subject><ispartof>International journal of sports medicine, 2022-06, Vol.43 (7), p.616-624</ispartof><rights>Thieme. All rights reserved.</rights><rights>Copyright Georg Thieme Verlag Stuttgart Jun 2022</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c352t-e82497fdcdcc47ef6ad5464195d9cc2283de2c9108db1a8e2b38ab53f8915f0a3</citedby><cites>FETCH-LOGICAL-c352t-e82497fdcdcc47ef6ad5464195d9cc2283de2c9108db1a8e2b38ab53f8915f0a3</cites><orcidid>0000-0001-7471-475X ; 0000-0002-6678-7964 ; 0000-0002-6234-4955 ; 0000-0002-0744-091X ; 0000-0002-1439-9935 ; 0000-0001-7003-399X ; 0000-0001-7417-4407 ; 0000-0002-2016-5852</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.thieme-connect.de/products/ejournals/pdf/10.1055/a-1699-2380.pdf$$EPDF$$P50$$Gthieme$$H</linktopdf><linktohtml>$$Uhttps://www.thieme-connect.de/products/ejournals/html/10.1055/a-1699-2380$$EHTML$$P50$$Gthieme$$H</linktohtml><link.rule.ids>314,776,780,3004,3005,27901,27902,54534,54535</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35114706$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lendeckel, Frederik</creatorcontrib><creatorcontrib>Zylla, Stephanie</creatorcontrib><creatorcontrib>Markus, Marcello Ricardo Paulista</creatorcontrib><creatorcontrib>Ewert, Ralf</creatorcontrib><creatorcontrib>Gläser, Sven</creatorcontrib><creatorcontrib>Völzke, Henry</creatorcontrib><creatorcontrib>Albrecht, Diana</creatorcontrib><creatorcontrib>Friedrich, Nele</creatorcontrib><creatorcontrib>Nauck, Matthias</creatorcontrib><creatorcontrib>Felix, Stephan B</creatorcontrib><creatorcontrib>Dörr, Marcus</creatorcontrib><creatorcontrib>Bahls, Martin</creatorcontrib><title>Association of Cardiopulmonary Exercise Capacity and Adipokines in the General Population</title><title>International journal of sports medicine</title><addtitle>Int J Sports Med</addtitle><description>Abstract
Adipokines and cardiorespiratory fitness (CRF) are associated with the
(patho)physiology of cardiometabolic diseases. Whether CRF and adipokines are
related is unclear. We investigated associations of CRF with leptin,
adiponectin, chemerin, resistin and vaspin. Data from the population-based Study
of Health in Pomerania was used (n=1,479; median age 49 years;
51% women). Cardiopulmonary exercise testing was used to measure CRF.
Circulating adipokine concentrations were measured by enzyme-linked
immunosorbent assay. The association between CRF and adipokines was assessed
using multivariable sex-specific quantile regression models. Higher maximum
oxygen uptake was significantly associated with lower leptin
(men:−0.11 ng/ml; 95%-confidence interval
[CI]:−0.18 to−0.03 ng/ml; p<0.005;
women:−0.17 ng/ml; 95%-CI:−0.33
to−0.02 ng/ml; p<0.05) and chemerin
(men:−0.26 ng/ml; 95%-CI:−0.52
to−0.01 ng/ml; p<0.05;
women:−0.41 ng/ml; 95%-CI:−0.82
to−0.01 ng/ml; p<0.05) as well as higher
adiponectin concentrations (men: 0.06 µg/ml;
95%-CI: 0.02 to 0.11 µg/ml; p<0.05;
women: 0.03 µg/ml; 95%-CI:−0.05 to
0.10 µg/ml; p=0.48). We found that CRF was
inversely associated with leptin and chemerin in both sexes and positively
associated with adiponectin only in men.</description><subject>Training & Testing</subject><issn>0172-4622</issn><issn>1439-3964</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNptkMtKxDAUQIMoOj5W7iXgRpRq3pMsh8EXCLrQhauSSW4x2jY1aUH_3o7jA8RVFvfcc8NBaJ-SU0qkPLMFVcYUjGuyhiZUcFNwo8Q6mhA6ZYVQjG2h7ZyfCaHCUL6JtrikVEyJmqDHWc7RBduH2OJY4blNPsRuqJvY2vSOz98guZBhHHTWhf4d29bjmQ9dfAktZBxa3D8BvoQWkq3x3XL307aLNipbZ9j7enfQw8X5_fyquLm9vJ7PbgrHJesL0EyYaeWdd05MoVLWS6EENdIb5xjT3ANzhhLtF9RqYAuu7ULyShsqK2L5DjpaebsUXwfIfdmE7KCubQtxyCVTTBHChdAjevgHfY5DasffjZSmkhGl1EidrCiXYs4JqrJLoRljlJSUy-KlLZfFy2XxkT74cg6LBvwP-514BI5XQP8UoIHfk__ZPgBbsYiX</recordid><startdate>202206</startdate><enddate>202206</enddate><creator>Lendeckel, Frederik</creator><creator>Zylla, Stephanie</creator><creator>Markus, Marcello Ricardo Paulista</creator><creator>Ewert, Ralf</creator><creator>Gläser, Sven</creator><creator>Völzke, Henry</creator><creator>Albrecht, Diana</creator><creator>Friedrich, Nele</creator><creator>Nauck, Matthias</creator><creator>Felix, Stephan B</creator><creator>Dörr, Marcus</creator><creator>Bahls, Martin</creator><general>Georg Thieme Verlag KG</general><general>Georg Thieme Verlag Stuttgart</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TS</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-7471-475X</orcidid><orcidid>https://orcid.org/0000-0002-6678-7964</orcidid><orcidid>https://orcid.org/0000-0002-6234-4955</orcidid><orcidid>https://orcid.org/0000-0002-0744-091X</orcidid><orcidid>https://orcid.org/0000-0002-1439-9935</orcidid><orcidid>https://orcid.org/0000-0001-7003-399X</orcidid><orcidid>https://orcid.org/0000-0001-7417-4407</orcidid><orcidid>https://orcid.org/0000-0002-2016-5852</orcidid></search><sort><creationdate>202206</creationdate><title>Association of Cardiopulmonary Exercise Capacity and Adipokines in the General Population</title><author>Lendeckel, Frederik ; Zylla, Stephanie ; Markus, Marcello Ricardo Paulista ; Ewert, Ralf ; Gläser, Sven ; Völzke, Henry ; Albrecht, Diana ; Friedrich, Nele ; Nauck, Matthias ; Felix, Stephan B ; Dörr, Marcus ; Bahls, Martin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c352t-e82497fdcdcc47ef6ad5464195d9cc2283de2c9108db1a8e2b38ab53f8915f0a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Training & Testing</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lendeckel, Frederik</creatorcontrib><creatorcontrib>Zylla, Stephanie</creatorcontrib><creatorcontrib>Markus, Marcello Ricardo Paulista</creatorcontrib><creatorcontrib>Ewert, Ralf</creatorcontrib><creatorcontrib>Gläser, Sven</creatorcontrib><creatorcontrib>Völzke, Henry</creatorcontrib><creatorcontrib>Albrecht, Diana</creatorcontrib><creatorcontrib>Friedrich, Nele</creatorcontrib><creatorcontrib>Nauck, Matthias</creatorcontrib><creatorcontrib>Felix, Stephan B</creatorcontrib><creatorcontrib>Dörr, Marcus</creatorcontrib><creatorcontrib>Bahls, Martin</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Physical Education Index</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of sports medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lendeckel, Frederik</au><au>Zylla, Stephanie</au><au>Markus, Marcello Ricardo Paulista</au><au>Ewert, Ralf</au><au>Gläser, Sven</au><au>Völzke, Henry</au><au>Albrecht, Diana</au><au>Friedrich, Nele</au><au>Nauck, Matthias</au><au>Felix, Stephan B</au><au>Dörr, Marcus</au><au>Bahls, Martin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Association of Cardiopulmonary Exercise Capacity and Adipokines in the General Population</atitle><jtitle>International journal of sports medicine</jtitle><addtitle>Int J Sports Med</addtitle><date>2022-06</date><risdate>2022</risdate><volume>43</volume><issue>7</issue><spage>616</spage><epage>624</epage><pages>616-624</pages><issn>0172-4622</issn><eissn>1439-3964</eissn><abstract>Abstract
Adipokines and cardiorespiratory fitness (CRF) are associated with the
(patho)physiology of cardiometabolic diseases. Whether CRF and adipokines are
related is unclear. We investigated associations of CRF with leptin,
adiponectin, chemerin, resistin and vaspin. Data from the population-based Study
of Health in Pomerania was used (n=1,479; median age 49 years;
51% women). Cardiopulmonary exercise testing was used to measure CRF.
Circulating adipokine concentrations were measured by enzyme-linked
immunosorbent assay. The association between CRF and adipokines was assessed
using multivariable sex-specific quantile regression models. Higher maximum
oxygen uptake was significantly associated with lower leptin
(men:−0.11 ng/ml; 95%-confidence interval
[CI]:−0.18 to−0.03 ng/ml; p<0.005;
women:−0.17 ng/ml; 95%-CI:−0.33
to−0.02 ng/ml; p<0.05) and chemerin
(men:−0.26 ng/ml; 95%-CI:−0.52
to−0.01 ng/ml; p<0.05;
women:−0.41 ng/ml; 95%-CI:−0.82
to−0.01 ng/ml; p<0.05) as well as higher
adiponectin concentrations (men: 0.06 µg/ml;
95%-CI: 0.02 to 0.11 µg/ml; p<0.05;
women: 0.03 µg/ml; 95%-CI:−0.05 to
0.10 µg/ml; p=0.48). We found that CRF was
inversely associated with leptin and chemerin in both sexes and positively
associated with adiponectin only in men.</abstract><cop>Rüdigerstraße 14, 70469 Stuttgart, Germany</cop><pub>Georg Thieme Verlag KG</pub><pmid>35114706</pmid><doi>10.1055/a-1699-2380</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0001-7471-475X</orcidid><orcidid>https://orcid.org/0000-0002-6678-7964</orcidid><orcidid>https://orcid.org/0000-0002-6234-4955</orcidid><orcidid>https://orcid.org/0000-0002-0744-091X</orcidid><orcidid>https://orcid.org/0000-0002-1439-9935</orcidid><orcidid>https://orcid.org/0000-0001-7003-399X</orcidid><orcidid>https://orcid.org/0000-0001-7417-4407</orcidid><orcidid>https://orcid.org/0000-0002-2016-5852</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0172-4622 |
| ispartof | International journal of sports medicine, 2022-06, Vol.43 (7), p.616-624 |
| issn | 0172-4622 1439-3964 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2626003448 |
| source | Thieme Connect Journals |
| subjects | Training & Testing |
| title | Association of Cardiopulmonary Exercise Capacity and Adipokines in the General Population |
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