Shedding new light on methylmercury-induced neurotoxicity through the crosstalk between autophagy and apoptosis

[Display omitted] •Summarizes the molecular mechanisms of autophagy and apoptosis in MeHg neurotoxicity.•Analyzes the relationship between autophagy and apoptosis in MeHg neurotoxicity.•Autophagic pathway may mitigate MeHg neurotoxicity through modulation of apoptosis. Methylmercury (MeHg) is a bio-...

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Veröffentlicht in:	Toxicology letters 2022-04, Vol.359, p.55-64
Hauptverfasser:	Ni, Linlin, Wei, Yanfeng, Pan, Jingjing, Li, Xiaoyang, Xu, Bin, Deng, Yu, Yang, Tianyao, Liu, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Apoptosis - drug effects Autophagy Autophagy - drug effects Crosstalk Disease Models, Animal Humans MeHg Metabolic Networks and Pathways Methylmercury Compounds - metabolism Methylmercury Compounds - toxicity Neurotoxicity Neurotoxicity Syndromes - etiology Neurotoxicity Syndromes - physiopathology
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