Rapid antibody conformational screening by matrix‐assisted laser desorption/ionization hydrogen‐deuterium exchange mass spectrometry

Recent advances in the field of cancer biology have accelerated the discovery and development of novel biopharmaceuticals. At the forefront of these drug development efforts are high‐throughput screening, compressed timelines, and limited sample quantities, all characteristic of the discovery space....

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Veröffentlicht in:Journal of separation science 2022-06, Vol.45 (12), p.2055-2063
Hauptverfasser: Mukherjee, Debopreeti, Trigo‐Mouriño, Pablo, Jiang, Yuan, Nowak, Timothy, Shchurik, Vladimir, Adpressa, Donovon A., Louie, Michael T., Reynolds, Shane R., Hohn, Michael J., Al‐Sayah, Mohammad Ahmed, Pirrone, Gregory F., Makarov, Alexey A.
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Sprache:eng
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