Limited power of dopamine transporter mRNA mapping for predicting dopamine transporter availability

Dopamine transporters (DAT) are transmembrane proteins that translocate dopamine from the extracellular space into presynaptic neurons. We aimed to investigate the predictive power of DAT mRNA for DAT protein expression, measured using positron emission tomography (PET). We performed 18F‐FP‐CIT PET...

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Veröffentlicht in:	Synapse (New York, N.Y.) N.Y.), 2022-04, Vol.76 (5-6), p.e22226-n/a
Hauptverfasser:	Pak, Kyoungjune, Seo, Seongho, Lee, Myung Jun, Im, Hyung‐Jun, Kim, Keunyoung, Kim, In Joo
Format:	Artikel
Sprache:	eng
Schlagworte:	Caudate nucleus Dopamine Dopamine - metabolism dopamine plasma membrane transport proteins Dopamine Plasma Membrane Transport Proteins - genetics Dopamine Plasma Membrane Transport Proteins - metabolism Dopamine transporter Gene expression Humans Membrane proteins messenger RNA Neostriatum Peptide mapping Positron emission tomography Probes Putamen Putamen - metabolism RNA, Messenger - metabolism
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