Hepatic veno-occlusive disease (sinusoidal obstruction syndrome) after hematopoietic stem cell transplantation in adult patients: Diagnosis, incidence, prophylaxis, and treatment

Hepatic veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) affecting the liver is a rare, possibly life-threatening complication of hematopoietic stem cell transplantation (HSCT). Sinusoidal endothelial cell (SEC) damage triggered by various factors (especially conditioning regimen) re...

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Veröffentlicht in:	Transfusion and apheresis science 2022-02, Vol.61 (1), p.103372-103372, Article 103372
Hauptverfasser:	Özkan, Hasan Atilla, Özkan, Sıdıka Gülkan
Format:	Artikel
Sprache:	eng
Schlagworte:	Defibrotide Hematopoietic Stem Cell Transplantation - adverse effects Hepatic Veno-Occlusive Disease - diagnosis Hepatic Veno-Occlusive Disease - physiopathology Hepatic Veno-Occlusive Disease - therapy Humans Incidence Liver stiffness measurement Methylprednisolone Risk Factors Sinusoidal obstruction syndrome Transplantation Conditioning - adverse effects Veno-occlusive disease
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