Impact of lymph node ratio on survival and recurrence outcomes in oral squamous cell carcinoma

Impact of lymph node ratio on survival and recurrence outcomes in oral squamous cell carcinoma

Growing evidence supports the lymph node ratio (LNR) as a prognostic factor for survival in patients with oral squamous cell carcinoma (OSCC). However, there is a lack of data regarding its association with recurrence outcomes. Data on 163 patients with OSCC who underwent primary surgical treatment...

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Veröffentlicht in:International journal of oral and maxillofacial surgery 2022-10, Vol.51 (10), p.1257-1263
Hauptverfasser: Mamic, M., Lucijanic, M., Lorencin, M., Suton, P., Luksic, I.
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Sprache:eng
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lymph node ratio
lymphatic metastasis
mouth neoplasms
neoplasm staging
survival analysis
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container_issue 10
container_start_page 1257
container_title International journal of oral and maxillofacial surgery
container_volume 51
creator Mamic, M.
Lucijanic, M.
Lorencin, M.
Suton, P.
Luksic, I.
description Growing evidence supports the lymph node ratio (LNR) as a prognostic factor for survival in patients with oral squamous cell carcinoma (OSCC). However, there is a lack of data regarding its association with recurrence outcomes. Data on 163 patients with OSCC who underwent primary surgical treatment at a tertiary centre between January 2009 and December 2015 were collected retrospectively and analysed. Receiver operating characteristic curve analysis was performed to determine optimal cut-off values for the survival analyses. Survival endpoints were disease progression/relapse for disease-free time (DFT), freedom from loco-regional recurrence (FLR), and freedom from distant metastasis (FDM), and as death from any cause for overall survival (OS). Patients with a lower LNR were found to have significantly superior DFT (LNR < 14%, P < 0.001), FLR (LNR
doi_str_mv 10.1016/j.ijom.2022.01.009
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subjects lymph node ratio
lymphatic metastasis
mouth neoplasms
neoplasm staging
survival analysis
title Impact of lymph node ratio on survival and recurrence outcomes in oral squamous cell carcinoma
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