Salt-Induced Hepatic Inflammatory Memory Contributes to Cardiovascular Damage Through Epigenetic Modulation of SIRT3

High salt intake is the leading dietary risk factor for cardiovascular diseases. Although clinical evidence suggests that high salt intake is associated with nonalcoholic fatty liver disease, which is an independent risk factor for cardiovascular diseases, it remains elusive whether salt-induced hep...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 2022-02, Vol.145 (5), p.375-391
Hauptverfasser:	Gao, Peng, You, Mei, Li, Li, Zhang, Qin, Fang, Xia, Wei, Xiao, Zhou, Qing, Zhang, Hexuan, Wang, Miao, Lu, Zongshi, Wang, Lijuan, Sun, Fang, Liu, Daoyan, Zheng, Hongting, Yan, Zhencheng, Yang, Gangyi, Zhu, Zhiming
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cardiovascular Diseases - chemically induced Cardiovascular Diseases - etiology Cardiovascular Diseases - pathology Epigenesis, Genetic - genetics Humans Inflammation - chemically induced Inflammation - etiology Inflammation - pathology Liver - pathology Mice Mice, Knockout Sirtuin 3 - genetics Sodium Chloride, Dietary - adverse effects
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