Estradiol-dependent gene expression profile in the amygdala of young ovariectomized spontaneously hypertensive rats

Estrogen plays a role in cardiovascular functions, emotional health, and energy homeostasis via estrogen receptors expressed in the brain. The comorbid relationship between rising blood pressure, a decline in mood and motivation, and body weight gain after menopause, when estrogen levels drop, sugge...

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Veröffentlicht in:	Physiological genomics 2022-03, Vol.54 (3), p.99-114
Hauptverfasser:	Pham, Linh T, Yamanaka, Ko, Miyamoto, Yasunori, Waki, Hidefumi, Gouraud, Sabine S S
Format:	Artikel
Sprache:	eng
Schlagworte:	17β-Estradiol Amygdala Amygdala - metabolism Animals Blood pressure Body Weight Body weight gain Dopamine receptors Energy balance Estradiol - pharmacology Estrogen receptors Estrogens Estrogens - metabolism Female Gene expression Homeostasis Humans Hypertension Limbic system Long-term depression Menopause Motivation Ovariectomy Physical activity Post-menopause Rats Rats, Inbred SHR Receptors, Estrogen - genetics Receptors, Estrogen - metabolism Rodents Synaptic depression Transcriptome - genetics Transcriptomics Young adults
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