TNFRSF10A downregulation induces retinal pigment epithelium degeneration during the pathogenesis of age-related macular degeneration and central serous chorioretinopathy

Abstract Age-related macular degeneration (AMD) and central serous chorioretinopathy (CSC) are common diseases that can cause vision loss in older and younger populations. These diseases share pathophysiological conditions derived from retinal pigment epithelium (RPE) dysfunction. Tumor necrosis fac...

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Veröffentlicht in:Human molecular genetics 2022-07, Vol.31 (13), p.2194-2206
Hauptverfasser: Mori, Kenichiro, Ishikawa, Keijiro, Fukuda, Yosuke, Ji, Rui, Wada, Iori, Kubo, Yuki, Akiyama, Masato, Notomi, Shoji, Murakami, Yusuke, Nakao, Shintaro, Arakawa, Satoshi, Shiose, Satomi, Hisatomi, Toshio, Yoshida, Shigeo, Kannan, Ram, Sonoda, Koh-Hei
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Sprache:eng
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