High plasma IL-6 levels following haploidentical allogeneic hematopoietic stem cell transplantation post-transplant cyclophosphamide as predictor of early death and worse outcome

Haploidentical hematopoietic stem cell transplantation (haplo-HSCT) can be used as an alternative procedure in the absence of HLA-compatible donors. The use of high doses of cyclophosphamide after infusion improves the prognosis and eliminates the need for T cell depletion in vivo. Among the main co...

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Veröffentlicht in:	Transplant immunology 2022-04, Vol.71, p.101543-101543, Article 101543
Hauptverfasser:	Farias, Mariela Granero, de Mello Vicente, Bruna, Habigzang, Muriel, Hirakata, Vania Naomi, de Oliveira da Silva, Priscila, Paz, Alessandra Aparecida, Daudt, Liane Esteves
Format:	Artikel
Sprache:	eng
Schlagworte:	Cyclophosphamide - therapeutic use Cytokine release syndrome Graft vs Host Disease GVHD Haploidentical hematopoietic stem cell transplantation Hematopoietic Stem Cell Transplantation - adverse effects Hematopoietic Stem Cell Transplantation - methods Humans IL-6 Interleukin-6 Neurotoxicity Transplantation, Haploidentical - adverse effects Transplantation, Haploidentical - methods
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