Boolean function metrics can assist modelers to check and choose logical rules

•A framework of Boolean function metrics for logical modeling.•Truth density reveals different output patterns for various Boolean functions.•Commonly used Boolean functions get more biased with increasing numbers of regulators.•Modelers can exploit a priori Boolean function bias to match observed d...

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Veröffentlicht in:	Journal of theoretical biology 2022-04, Vol.538, p.111025-111025, Article 111025
Hauptverfasser:	Zobolas, John, Monteiro, Pedro T., Kuiper, Martin, Flobak, Åsmund
Format:	Artikel
Sprache:	eng
Schlagworte:	Benchmarking Bias Boolean functions Boolean regulatory networks Complexity Gene Regulatory Networks Logic Signal Transduction Truth Density
Online-Zugang:	Volltext
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