Development and application of Cas13a-based diagnostic assay for Neisseria gonorrhoeae detection and azithromycin resistance identification

Abstract Background Gonorrhoea, caused by Neisseria gonorrhoeae, has spread worldwide. Strains resistant to most antibiotics, including ceftriaxone and azithromycin, have emerged to an alarming level. Rapid testing for N. gonorrhoeae and its antimicrobial resistance will therefore contribute to clin...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 2022-02, Vol.77 (3), p.656-664
Hauptverfasser:	Luo, Hao, Chen, Wentao, Mai, Zhida, Yang, Jianjiang, Lin, Xiaomian, Zeng, Lihong, Pan, Yuying, Xie, Qinghui, Xu, Qingqing, Li, Xiaoxiao, Liao, Yiwen, Feng, Zhanqin, Ou, Jiangli, Qin, Xiaolin, Zheng, Heping
Format:	Artikel
Sprache:	eng
Schlagworte:	Azithromycin - pharmacology Drug Resistance, Bacterial - genetics Gonorrhea - diagnosis Humans Microbial Sensitivity Tests Neisseria gonorrhoeae
Online-Zugang:	Volltext
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