Engineered exosome as targeted lncRNA MEG3 delivery vehicles for osteosarcoma therapy

Exosomes as nanosized membrane vesicles, could targeted deliver therapeutic agents by modification with target ligands. Exosome-derived non-coding RNAs play a vital role in the development of tumors. Previous evidences reveal that long non-coding RNA maternally expressed gene 3 (lncRNA MEG3) has ant...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of controlled release 2022-03, Vol.343, p.107-117
Hauptverfasser:	Huang, Xin, Wu, Wei, Jing, Doudou, Yang, Lingkai, Guo, Haoyu, Wang, Lutong, Zhang, Weiyue, Pu, Feifei, Shao, Zengwu
Format:	Artikel
Sprache:	eng
Schlagworte:	Bone Neoplasms - genetics Bone Neoplasms - therapy Engineered exosome Exosomes - genetics Exosomes - pathology Humans LncRNA MEG3 Osteosarcoma Osteosarcoma - genetics Osteosarcoma - therapy RNA, Long Noncoding - genetics Tumor-targeting therapy
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!