Anti-Lea monoclonal antibody SPM 522 recognizes an extended Lea epitope

[Display omitted] Insights into the differential binding characteristics of anti-Lea and anti-LeaLex monoclonal antibodies (mAbs) provide information to develop LeaLex-based cancer immunotherapeutics while avoiding anti-Lea autoimmune reactions. We characterized the epitope recognized by anti-Lea mA...

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Veröffentlicht in:	Bioorganic & medicinal chemistry 2022-02, Vol.56, p.116628-116628, Article 116628
Hauptverfasser:	Jegatheeswaran, Sinthuja, Guillemineau, Mickael, Giovane, Richard, Borrillo, Louis, Liao, Liang, Kuir, Deng, Auzanneau, France-Isabelle
Format:	Artikel
Sprache:	eng
Schlagworte:	ELISA Lewis A LewisALewisX SPM522 epitope Tumor-associated carbohydrate antigens
Online-Zugang:	Volltext
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