The anti-fatigue effect of the Auxis thazard oligopeptide via modulation of the AMPK/PGC-1α pathway in mice

The oligopeptide (ATO) was obtained by papain digestion and ultrafiltration membrane separation, and its anti-fatigue effects and mechanisms were evaluated using animal experiments on Kunming mice. Compared with the negative control group, the ATO extended the time to exhaustion in mice in a forced...

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Veröffentlicht in:	Food & function 2022-02, Vol.13 (3), p.1641-1650
Hauptverfasser:	Qu, Yushan, Ji, Hongwu, Song, Wenkui, Peng, Shuo, Zhan, Suhong, Wei, Liuyi, Chen, Ming, Zhang, Di, Liu, Shucheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Outbred Strains Antioxidants Auxis thazard Behavior, Animal - drug effects Disease Models, Animal Energy metabolism Fatigue Fishes Gene expression Glycogen Glycogens Lactic acid Liver Malondialdehyde Membrane separation Mice Muscle Fatigue - drug effects Muscles Myocardium Oligopeptides - pharmacology Oligopeptides - therapeutic use Oxidative metabolism Oxidative stress Papain Specific Pathogen-Free Organisms Swimming Ultrafiltration Urea
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