Efficacy of pulsed electromagnetic field on pain and physical function in patients with low back pain: A systematic review and meta-analysis

Objective To assess the effectiveness of pulsed electromagnetic field (PEMF) on pain and physical function in patients with low back pain. Data sources A search of PubMed, Embase, Cochrane Library, and Web of Science was conducted up to December 2021. Methods We included randomized controlled trials...

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Veröffentlicht in:Clinical rehabilitation 2022-05, Vol.36 (5), p.636-649
Hauptverfasser: Sun, Xin, Huang, Liyi, Wang, Lu, Fu, Chenying, Zhang, Qing, Cheng, Hongxin, Pei, Gaiqin, Wang, Yang, He, Chengqi, Wei, Quan
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container_end_page 649
container_issue 5
container_start_page 636
container_title Clinical rehabilitation
container_volume 36
creator Sun, Xin
Huang, Liyi
Wang, Lu
Fu, Chenying
Zhang, Qing
Cheng, Hongxin
Pei, Gaiqin
Wang, Yang
He, Chengqi
Wei, Quan
description Objective To assess the effectiveness of pulsed electromagnetic field (PEMF) on pain and physical function in patients with low back pain. Data sources A search of PubMed, Embase, Cochrane Library, and Web of Science was conducted up to December 2021. Methods We included randomized controlled trials that investigated the effectiveness of PEMF in patients with low back pain. The primary outcome was pain intensity and the secondary outcome was physical function, both were evaluated by assessment scales. Standardized mean difference (SMD) and 95% confidence interval (CI) were calculated for the summary statistics analysis. The registration number of this systematic review in PROSPERO is CRD42020213829. Results Fourteen trials involving 618 participants were included. The PEMF treatment showed more significant pain alleviation than placebo or other therapy alone in patients with low back pain (SMD = −1.01, 95% CI −1.42 to −0.6, P 
doi_str_mv 10.1177/02692155221074052
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Data sources A search of PubMed, Embase, Cochrane Library, and Web of Science was conducted up to December 2021. Methods We included randomized controlled trials that investigated the effectiveness of PEMF in patients with low back pain. The primary outcome was pain intensity and the secondary outcome was physical function, both were evaluated by assessment scales. Standardized mean difference (SMD) and 95% confidence interval (CI) were calculated for the summary statistics analysis. The registration number of this systematic review in PROSPERO is CRD42020213829. Results Fourteen trials involving 618 participants were included. The PEMF treatment showed more significant pain alleviation than placebo or other therapy alone in patients with low back pain (SMD = −1.01, 95% CI −1.42 to −0.6, P &lt; 0.001, I2 = 31%; SMD = −0.36, 95% CI −0.62 to −0.11, P = 0.005, I2 = 37%, respectively.) In addition, a significant difference in pain alleviation was observed in patients with chronic low back pain (SMD = −0.6, 95%CI − 0.94 to −0.25, p &lt; 0.001, I2 = 67%), whereas no significant difference was observed in patients with acute low back pain (SMD = −0.46, 95%CI − 0.99 to 0.07, p = 0.09, I2 = 0%). PEMF did not improve physical function compared with the control treatment (SMD = −0.45, 95% CI − 0.98 to 0.07, p = 0.09, I2 = 86%). Conclusion PEMF is beneficial for alleviating pain in patients with chronic low back pain despite having no advantage in improving physical function.</description><identifier>ISSN: 0269-2155</identifier><identifier>EISSN: 1477-0873</identifier><identifier>DOI: 10.1177/02692155221074052</identifier><identifier>PMID: 35077249</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Alleviation ; Back pain ; Chronic back pain ; Chronic low back pain ; Clinical trials ; Efficacy ; Electromagnetic Fields ; Electromagnetic waves ; Electromagnetism ; Humans ; Low Back Pain - therapy ; Meta-analysis ; Physical ability ; Physical therapy ; Rehabilitation ; Systematic review</subject><ispartof>Clinical rehabilitation, 2022-05, Vol.36 (5), p.636-649</ispartof><rights>The Author(s) 2022</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c368t-e5ee5cf6aabf20409880e585b4c4a993d55b8776627c942c1d0582b3f6595d923</citedby><cites>FETCH-LOGICAL-c368t-e5ee5cf6aabf20409880e585b4c4a993d55b8776627c942c1d0582b3f6595d923</cites><orcidid>0000-0003-2639-7416 ; 0000-0002-7057-8292 ; 0000-0002-0541-905X ; 0000-0003-3845-4342</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/02692155221074052$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/02692155221074052$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,776,780,21799,27903,27904,30978,43600,43601</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35077249$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sun, Xin</creatorcontrib><creatorcontrib>Huang, Liyi</creatorcontrib><creatorcontrib>Wang, Lu</creatorcontrib><creatorcontrib>Fu, Chenying</creatorcontrib><creatorcontrib>Zhang, Qing</creatorcontrib><creatorcontrib>Cheng, Hongxin</creatorcontrib><creatorcontrib>Pei, Gaiqin</creatorcontrib><creatorcontrib>Wang, Yang</creatorcontrib><creatorcontrib>He, Chengqi</creatorcontrib><creatorcontrib>Wei, Quan</creatorcontrib><title>Efficacy of pulsed electromagnetic field on pain and physical function in patients with low back pain: A systematic review and meta-analysis</title><title>Clinical rehabilitation</title><addtitle>Clin Rehabil</addtitle><description>Objective To assess the effectiveness of pulsed electromagnetic field (PEMF) on pain and physical function in patients with low back pain. Data sources A search of PubMed, Embase, Cochrane Library, and Web of Science was conducted up to December 2021. Methods We included randomized controlled trials that investigated the effectiveness of PEMF in patients with low back pain. The primary outcome was pain intensity and the secondary outcome was physical function, both were evaluated by assessment scales. Standardized mean difference (SMD) and 95% confidence interval (CI) were calculated for the summary statistics analysis. The registration number of this systematic review in PROSPERO is CRD42020213829. Results Fourteen trials involving 618 participants were included. The PEMF treatment showed more significant pain alleviation than placebo or other therapy alone in patients with low back pain (SMD = −1.01, 95% CI −1.42 to −0.6, P &lt; 0.001, I2 = 31%; SMD = −0.36, 95% CI −0.62 to −0.11, P = 0.005, I2 = 37%, respectively.) In addition, a significant difference in pain alleviation was observed in patients with chronic low back pain (SMD = −0.6, 95%CI − 0.94 to −0.25, p &lt; 0.001, I2 = 67%), whereas no significant difference was observed in patients with acute low back pain (SMD = −0.46, 95%CI − 0.99 to 0.07, p = 0.09, I2 = 0%). PEMF did not improve physical function compared with the control treatment (SMD = −0.45, 95% CI − 0.98 to 0.07, p = 0.09, I2 = 86%). Conclusion PEMF is beneficial for alleviating pain in patients with chronic low back pain despite having no advantage in improving physical function.</description><subject>Alleviation</subject><subject>Back pain</subject><subject>Chronic back pain</subject><subject>Chronic low back pain</subject><subject>Clinical trials</subject><subject>Efficacy</subject><subject>Electromagnetic Fields</subject><subject>Electromagnetic waves</subject><subject>Electromagnetism</subject><subject>Humans</subject><subject>Low Back Pain - therapy</subject><subject>Meta-analysis</subject><subject>Physical ability</subject><subject>Physical therapy</subject><subject>Rehabilitation</subject><subject>Systematic review</subject><issn>0269-2155</issn><issn>1477-0873</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>7QJ</sourceid><recordid>eNp1kc1OJCEURonRaI_6AG4mJG7clAIFBbgzHR0nMXGj6wpFXRSn_qag7PQ7-NBStjrJGFcsvvMdbu5F6IiSU0qlPCOs0IwKwRglkhPBttCCcikzomS-jRZzns3AHvoRwhMhRDFOd9FeLoiUjOsFerl0zltj17h3eJiaADWGBmwc-9Y8dBC9xc5DU-O-w4PxHTZdjYfHdUitBrups9GnyM9p9NDFgFc-PuKmX-HK2D9vpXN8gcM6RGjNLBzh2cPqzdRCNJnpTJOE4QDtOJNGOHx_99H91eXd8jq7uf31e3lxk9m8UDEDASCsK4ypHCOcaKUICCUqbrnROq-FqJSURcGk1ZxZWhOhWJW7QmhRa5bvo5ONdxj7vxOEWLY-WGga00E_hZIVjOki7ZQm9Pg_9KmfxjTvTHGqCOFiFtINZcc-hBFcOYy-NeO6pKScT1V-OVXq_Hw3T1UL9Wfj4zYJON0AwTzAv2-_N74C_omb3Q</recordid><startdate>202205</startdate><enddate>202205</enddate><creator>Sun, Xin</creator><creator>Huang, Liyi</creator><creator>Wang, Lu</creator><creator>Fu, Chenying</creator><creator>Zhang, Qing</creator><creator>Cheng, Hongxin</creator><creator>Pei, Gaiqin</creator><creator>Wang, Yang</creator><creator>He, Chengqi</creator><creator>Wei, Quan</creator><general>SAGE Publications</general><general>Sage Publications Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QJ</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-2639-7416</orcidid><orcidid>https://orcid.org/0000-0002-7057-8292</orcidid><orcidid>https://orcid.org/0000-0002-0541-905X</orcidid><orcidid>https://orcid.org/0000-0003-3845-4342</orcidid></search><sort><creationdate>202205</creationdate><title>Efficacy of pulsed electromagnetic field on pain and physical function in patients with low back pain: A systematic review and meta-analysis</title><author>Sun, Xin ; Huang, Liyi ; Wang, Lu ; Fu, Chenying ; Zhang, Qing ; Cheng, Hongxin ; Pei, Gaiqin ; Wang, Yang ; He, Chengqi ; Wei, Quan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c368t-e5ee5cf6aabf20409880e585b4c4a993d55b8776627c942c1d0582b3f6595d923</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Alleviation</topic><topic>Back pain</topic><topic>Chronic back pain</topic><topic>Chronic low back pain</topic><topic>Clinical trials</topic><topic>Efficacy</topic><topic>Electromagnetic Fields</topic><topic>Electromagnetic waves</topic><topic>Electromagnetism</topic><topic>Humans</topic><topic>Low Back Pain - therapy</topic><topic>Meta-analysis</topic><topic>Physical ability</topic><topic>Physical therapy</topic><topic>Rehabilitation</topic><topic>Systematic review</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sun, Xin</creatorcontrib><creatorcontrib>Huang, Liyi</creatorcontrib><creatorcontrib>Wang, Lu</creatorcontrib><creatorcontrib>Fu, Chenying</creatorcontrib><creatorcontrib>Zhang, Qing</creatorcontrib><creatorcontrib>Cheng, Hongxin</creatorcontrib><creatorcontrib>Pei, Gaiqin</creatorcontrib><creatorcontrib>Wang, Yang</creatorcontrib><creatorcontrib>He, Chengqi</creatorcontrib><creatorcontrib>Wei, Quan</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Applied Social Sciences Index &amp; Abstracts (ASSIA)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical rehabilitation</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sun, Xin</au><au>Huang, Liyi</au><au>Wang, Lu</au><au>Fu, Chenying</au><au>Zhang, Qing</au><au>Cheng, Hongxin</au><au>Pei, Gaiqin</au><au>Wang, Yang</au><au>He, Chengqi</au><au>Wei, Quan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Efficacy of pulsed electromagnetic field on pain and physical function in patients with low back pain: A systematic review and meta-analysis</atitle><jtitle>Clinical rehabilitation</jtitle><addtitle>Clin Rehabil</addtitle><date>2022-05</date><risdate>2022</risdate><volume>36</volume><issue>5</issue><spage>636</spage><epage>649</epage><pages>636-649</pages><issn>0269-2155</issn><eissn>1477-0873</eissn><abstract>Objective To assess the effectiveness of pulsed electromagnetic field (PEMF) on pain and physical function in patients with low back pain. Data sources A search of PubMed, Embase, Cochrane Library, and Web of Science was conducted up to December 2021. Methods We included randomized controlled trials that investigated the effectiveness of PEMF in patients with low back pain. The primary outcome was pain intensity and the secondary outcome was physical function, both were evaluated by assessment scales. Standardized mean difference (SMD) and 95% confidence interval (CI) were calculated for the summary statistics analysis. The registration number of this systematic review in PROSPERO is CRD42020213829. Results Fourteen trials involving 618 participants were included. The PEMF treatment showed more significant pain alleviation than placebo or other therapy alone in patients with low back pain (SMD = −1.01, 95% CI −1.42 to −0.6, P &lt; 0.001, I2 = 31%; SMD = −0.36, 95% CI −0.62 to −0.11, P = 0.005, I2 = 37%, respectively.) In addition, a significant difference in pain alleviation was observed in patients with chronic low back pain (SMD = −0.6, 95%CI − 0.94 to −0.25, p &lt; 0.001, I2 = 67%), whereas no significant difference was observed in patients with acute low back pain (SMD = −0.46, 95%CI − 0.99 to 0.07, p = 0.09, I2 = 0%). PEMF did not improve physical function compared with the control treatment (SMD = −0.45, 95% CI − 0.98 to 0.07, p = 0.09, I2 = 86%). Conclusion PEMF is beneficial for alleviating pain in patients with chronic low back pain despite having no advantage in improving physical function.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>35077249</pmid><doi>10.1177/02692155221074052</doi><tpages>14</tpages><orcidid>https://orcid.org/0000-0003-2639-7416</orcidid><orcidid>https://orcid.org/0000-0002-7057-8292</orcidid><orcidid>https://orcid.org/0000-0002-0541-905X</orcidid><orcidid>https://orcid.org/0000-0003-3845-4342</orcidid></addata></record>
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source MEDLINE; SAGE Complete; Applied Social Sciences Index & Abstracts (ASSIA)
subjects Alleviation
Back pain
Chronic back pain
Chronic low back pain
Clinical trials
Efficacy
Electromagnetic Fields
Electromagnetic waves
Electromagnetism
Humans
Low Back Pain - therapy
Meta-analysis
Physical ability
Physical therapy
Rehabilitation
Systematic review
title Efficacy of pulsed electromagnetic field on pain and physical function in patients with low back pain: A systematic review and meta-analysis
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