Bioavailability and trophic magnification of antibiotics in aquatic food webs of Pearl River, China: Influence of physicochemical characteristics and biotransformation
Information on trophodynamics of antibiotics and subsequent relationships to antibiotic metabolism in river ecosystem is still unavailable, limiting the evaluation of their bioaccumulation and trophodynamics in aquatic food webs. In the present study, concentrations and relative abundance of 11 anti...
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| Veröffentlicht in: | The Science of the total environment 2022-05, Vol.820, p.153285-153285, Article 153285 |
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| creator | Tang, Jinpeng Zhang, Jinhua Su, Linhui Jia, Yanyan Yang, Yang |
| description | Information on trophodynamics of antibiotics and subsequent relationships to antibiotic metabolism in river ecosystem is still unavailable, limiting the evaluation of their bioaccumulation and trophodynamics in aquatic food webs. In the present study, concentrations and relative abundance of 11 antibiotics were investigated in surface water, sediment and 22 aquatic taxa (e.g., fish, invertebrates and plankton) from Pearl River, South China. The logarithmic bioaccumulation factors (log BAFs) of antibiotics generally showed positive relationships with their log D (pH-adjusted log Kow), implying that their bioaccumulation of ionizable antibiotics depends on it is in an ionized form. Higher BAFs of antibiotics in benthic biota were observed than those in fish, indicating that sediment ingestion was a possible route of antibiotic exposure. The logarithmic biota-sediment accumulation factors (log BSAFs) of benthic biota increased when log D increased from −4.79 to −0.01, but declined thereafter. Trophodynamics of antibiotics was investigated, and intrinsic clearance were measured in liver microsomes of Tilapia zillii (trophic level [TL]: 2.5), Anabas testudineu (TL: 3.9), and Coilia grayi (TL: 5.0). Only ciprofloxacin (CFX) showed significant trophic magnification (Trophic Magnification Factor [TMF] = 1.95), and a higher metabolism rate in lower trophic levels suggest that metabolic biotransformation play a significant role in driving biomagnification of antibiotics.
[Display omitted]
•Antibiotic profiles in plankton, benthic invertebrates and fish are different.•Higher bioaccumulation factor of antibiotics observed in invertebrates than in fish.•Antibiotic biota-sediment accumulation factor was biphasic correlated with log D.•Ciprofloxacin biomagnifies in food web with trophic magnification factor of 1.95.•Metabolisms by different fish may influence biomagnification of antibiotics. |
| doi_str_mv | 10.1016/j.scitotenv.2022.153285 |
| format | Article |
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[Display omitted]
•Antibiotic profiles in plankton, benthic invertebrates and fish are different.•Higher bioaccumulation factor of antibiotics observed in invertebrates than in fish.•Antibiotic biota-sediment accumulation factor was biphasic correlated with log D.•Ciprofloxacin biomagnifies in food web with trophic magnification factor of 1.95.•Metabolisms by different fish may influence biomagnification of antibiotics.</description><identifier>ISSN: 0048-9697</identifier><identifier>EISSN: 1879-1026</identifier><identifier>DOI: 10.1016/j.scitotenv.2022.153285</identifier><identifier>PMID: 35066051</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Animals ; Anti-Bacterial Agents - metabolism ; Antibiotics ; Bioaccumulation ; Biological Availability ; Biomagnification ; Biotransformation ; China ; Ecosystem ; Environmental Monitoring ; Fishes - metabolism ; Food Chain ; Liver S9 ; Metabolism ; Rivers ; Water Pollutants, Chemical - analysis</subject><ispartof>The Science of the total environment, 2022-05, Vol.820, p.153285-153285, Article 153285</ispartof><rights>2022</rights><rights>Copyright © 2022. Published by Elsevier B.V.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c371t-83c7f31e99f73d64a45ea1b7be989744ad9ee1d030aa6dfc71f79d0a5ffd4a113</citedby><cites>FETCH-LOGICAL-c371t-83c7f31e99f73d64a45ea1b7be989744ad9ee1d030aa6dfc71f79d0a5ffd4a113</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.scitotenv.2022.153285$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35066051$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tang, Jinpeng</creatorcontrib><creatorcontrib>Zhang, Jinhua</creatorcontrib><creatorcontrib>Su, Linhui</creatorcontrib><creatorcontrib>Jia, Yanyan</creatorcontrib><creatorcontrib>Yang, Yang</creatorcontrib><title>Bioavailability and trophic magnification of antibiotics in aquatic food webs of Pearl River, China: Influence of physicochemical characteristics and biotransformation</title><title>The Science of the total environment</title><addtitle>Sci Total Environ</addtitle><description>Information on trophodynamics of antibiotics and subsequent relationships to antibiotic metabolism in river ecosystem is still unavailable, limiting the evaluation of their bioaccumulation and trophodynamics in aquatic food webs. In the present study, concentrations and relative abundance of 11 antibiotics were investigated in surface water, sediment and 22 aquatic taxa (e.g., fish, invertebrates and plankton) from Pearl River, South China. The logarithmic bioaccumulation factors (log BAFs) of antibiotics generally showed positive relationships with their log D (pH-adjusted log Kow), implying that their bioaccumulation of ionizable antibiotics depends on it is in an ionized form. Higher BAFs of antibiotics in benthic biota were observed than those in fish, indicating that sediment ingestion was a possible route of antibiotic exposure. The logarithmic biota-sediment accumulation factors (log BSAFs) of benthic biota increased when log D increased from −4.79 to −0.01, but declined thereafter. Trophodynamics of antibiotics was investigated, and intrinsic clearance were measured in liver microsomes of Tilapia zillii (trophic level [TL]: 2.5), Anabas testudineu (TL: 3.9), and Coilia grayi (TL: 5.0). Only ciprofloxacin (CFX) showed significant trophic magnification (Trophic Magnification Factor [TMF] = 1.95), and a higher metabolism rate in lower trophic levels suggest that metabolic biotransformation play a significant role in driving biomagnification of antibiotics.
[Display omitted]
•Antibiotic profiles in plankton, benthic invertebrates and fish are different.•Higher bioaccumulation factor of antibiotics observed in invertebrates than in fish.•Antibiotic biota-sediment accumulation factor was biphasic correlated with log D.•Ciprofloxacin biomagnifies in food web with trophic magnification factor of 1.95.•Metabolisms by different fish may influence biomagnification of antibiotics.</description><subject>Animals</subject><subject>Anti-Bacterial Agents - metabolism</subject><subject>Antibiotics</subject><subject>Bioaccumulation</subject><subject>Biological Availability</subject><subject>Biomagnification</subject><subject>Biotransformation</subject><subject>China</subject><subject>Ecosystem</subject><subject>Environmental Monitoring</subject><subject>Fishes - metabolism</subject><subject>Food Chain</subject><subject>Liver S9</subject><subject>Metabolism</subject><subject>Rivers</subject><subject>Water Pollutants, Chemical - analysis</subject><issn>0048-9697</issn><issn>1879-1026</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU1v1DAQhi0EokvhL4CPHMhi58sxt3bFR6VKIATnaGKPyaySeGs7i_YX8TdJuqVX5jKHeeZ9x34ZeyPFVgpZv99vo6HkE07HbS7yfCurIm-qJ2wjG6UzKfL6KdsIUTaZrrW6YC9i3IulVCOfs4uiEnUtKrlhf67JwxFogI4GSicOk-Up-ENPho_wayJHBhL5iXu3DBN15BOZyGnicDcvI8Od95b_xi6uzDeEMPDvdMTwju96muADv5ncMONkcAUO_SmS8abHcZEeuOkhgEkYKN4LrxesJgGm6HwY791fsmcOhoivHvol-_np44_dl-z26-eb3dVtZgolU9YURrlCotZOFbYuoawQZKc61I1WZQlWI0orCgFQW2eUdEpbAZVztgQpi0v29qx7CP5uxpjakaLBYYAJ_RzbvM7zUtWV1AuqzqgJPsaArj0EGiGcWinaNaV23z6m1K4pteeUls3XDyZzN6J93PsXywJcnQFcnnokDKvQ-n-WAprUWk__NfkLX_OtIg</recordid><startdate>20220510</startdate><enddate>20220510</enddate><creator>Tang, Jinpeng</creator><creator>Zhang, Jinhua</creator><creator>Su, Linhui</creator><creator>Jia, Yanyan</creator><creator>Yang, Yang</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20220510</creationdate><title>Bioavailability and trophic magnification of antibiotics in aquatic food webs of Pearl River, China: Influence of physicochemical characteristics and biotransformation</title><author>Tang, Jinpeng ; Zhang, Jinhua ; Su, Linhui ; Jia, Yanyan ; Yang, Yang</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c371t-83c7f31e99f73d64a45ea1b7be989744ad9ee1d030aa6dfc71f79d0a5ffd4a113</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Animals</topic><topic>Anti-Bacterial Agents - metabolism</topic><topic>Antibiotics</topic><topic>Bioaccumulation</topic><topic>Biological Availability</topic><topic>Biomagnification</topic><topic>Biotransformation</topic><topic>China</topic><topic>Ecosystem</topic><topic>Environmental Monitoring</topic><topic>Fishes - metabolism</topic><topic>Food Chain</topic><topic>Liver S9</topic><topic>Metabolism</topic><topic>Rivers</topic><topic>Water Pollutants, Chemical - analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tang, Jinpeng</creatorcontrib><creatorcontrib>Zhang, Jinhua</creatorcontrib><creatorcontrib>Su, Linhui</creatorcontrib><creatorcontrib>Jia, Yanyan</creatorcontrib><creatorcontrib>Yang, Yang</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Science of the total environment</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tang, Jinpeng</au><au>Zhang, Jinhua</au><au>Su, Linhui</au><au>Jia, Yanyan</au><au>Yang, Yang</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Bioavailability and trophic magnification of antibiotics in aquatic food webs of Pearl River, China: Influence of physicochemical characteristics and biotransformation</atitle><jtitle>The Science of the total environment</jtitle><addtitle>Sci Total Environ</addtitle><date>2022-05-10</date><risdate>2022</risdate><volume>820</volume><spage>153285</spage><epage>153285</epage><pages>153285-153285</pages><artnum>153285</artnum><issn>0048-9697</issn><eissn>1879-1026</eissn><abstract>Information on trophodynamics of antibiotics and subsequent relationships to antibiotic metabolism in river ecosystem is still unavailable, limiting the evaluation of their bioaccumulation and trophodynamics in aquatic food webs. In the present study, concentrations and relative abundance of 11 antibiotics were investigated in surface water, sediment and 22 aquatic taxa (e.g., fish, invertebrates and plankton) from Pearl River, South China. The logarithmic bioaccumulation factors (log BAFs) of antibiotics generally showed positive relationships with their log D (pH-adjusted log Kow), implying that their bioaccumulation of ionizable antibiotics depends on it is in an ionized form. Higher BAFs of antibiotics in benthic biota were observed than those in fish, indicating that sediment ingestion was a possible route of antibiotic exposure. The logarithmic biota-sediment accumulation factors (log BSAFs) of benthic biota increased when log D increased from −4.79 to −0.01, but declined thereafter. Trophodynamics of antibiotics was investigated, and intrinsic clearance were measured in liver microsomes of Tilapia zillii (trophic level [TL]: 2.5), Anabas testudineu (TL: 3.9), and Coilia grayi (TL: 5.0). Only ciprofloxacin (CFX) showed significant trophic magnification (Trophic Magnification Factor [TMF] = 1.95), and a higher metabolism rate in lower trophic levels suggest that metabolic biotransformation play a significant role in driving biomagnification of antibiotics.
[Display omitted]
•Antibiotic profiles in plankton, benthic invertebrates and fish are different.•Higher bioaccumulation factor of antibiotics observed in invertebrates than in fish.•Antibiotic biota-sediment accumulation factor was biphasic correlated with log D.•Ciprofloxacin biomagnifies in food web with trophic magnification factor of 1.95.•Metabolisms by different fish may influence biomagnification of antibiotics.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>35066051</pmid><doi>10.1016/j.scitotenv.2022.153285</doi><tpages>1</tpages></addata></record> |
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| subjects | Animals Anti-Bacterial Agents - metabolism Antibiotics Bioaccumulation Biological Availability Biomagnification Biotransformation China Ecosystem Environmental Monitoring Fishes - metabolism Food Chain Liver S9 Metabolism Rivers Water Pollutants, Chemical - analysis |
| title | Bioavailability and trophic magnification of antibiotics in aquatic food webs of Pearl River, China: Influence of physicochemical characteristics and biotransformation |
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