The significance of the SDF-1/CXCR4 signaling pathway in the normal development

Chemokines are chemoattractants that can regulate cell movement and adhesion. SDF-1 [stromal cell-derived factor-1 (SDF-1)] is a homeostatic CXC chemokine. SDF-1 and its receptors [CXC chemokine receptor 4 (CXCR4)] form a signaling pathway that plays critical roles in different pathological and phys...

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Veröffentlicht in:	Molecular biology reports 2022-04, Vol.49 (4), p.3307-3320
Hauptverfasser:	Sadri, Farzad, Rezaei, Zohreh, Fereidouni, Mohammad
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Animal Anatomy Animal Biochemistry Biomedical and Life Sciences Cell Movement - physiology Chemokine CXCL12 Chemokine receptors Chemokines Chemotactic factors CXC chemokines CXCR4 protein Embryogenesis Histology Humans Life Sciences Morphology Neoplasms - metabolism Neovascularization, Pathologic Receptors, CXCR4 - genetics Receptors, CXCR4 - metabolism Review SDF-1 protein Signal Transduction Tumors Wound healing
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