Esophageal and gastric malignancies after bariatric surgery: a retrospective global study
Bariatric surgery can influence the presentation, diagnosis, and management of gastrointestinal cancers. Esophagogastric (EG) malignancies in patients who have had a prior bariatric procedure have not been fully characterized. To characterize EG malignancies after bariatric procedures. University Ho...
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| Veröffentlicht in: | Surgery for obesity and related diseases 2022-04, Vol.18 (4), p.464-472 |
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| creator | Parmar, Chetan Zakeri, Roxanna Abouelazayem, Mohamed Shin, Thomas H. Aminian, Ali Abu Dayyeh, Barham K. Wee, Melissa Y. Fischer, Laura Daams, Freek Mahawar, Kamal Agustin, Cataldo Fuente, Ignacio Carbajo, Miguel Cal, Patricio Chisholm, Jacob Tan, Michael H.L. Gan, Philip Gananadha, Sivakumar Felsenreich, Daniel M. Prager, Gerhard Matthys, Chris Himpens, Jacques M. Focquet, Marc A.M.R.M. Ramos, Almino Nato, Manoel Galvano Vidal, Thiago Andalib, Amin Siblini, Aya Ferri, Lorenzo Abdarabo, Lina Pescarus, Radu Yang, Wah Hamed, Hosam Bergeat, Damien Marie, De Montrichard Martini, Francesco Regis, François Genser, Laurent Skalli, Mehdi Nedelcu, Marius Smejkal, Milan Kassir, Radwan Nicolas, Regenet Stier, Christine Kermansaravi, Mohammad Raziel, Asnat Sakran, Nasser Oldani, Alberto Boru, Cristian Eugeniu Mécheri, Fouzia Ciccarese, Francesca Cesana, Giovanni Carlo Musella, Mario Foletto, Mirto Auricchio, Pasquale Olmi, Stefano Seki, Yosuke Van 'T Hof, Gerhard Hart, Judith W.H. Van De Sande, Justin S.L. Takkenberg, Marijn Snoekx, Rob Plat, Victor D. Kalinowski, Piotr Nabais, Celso Al-Bahrani, Ahmed Z. Al Zoubi, Mohammad Bettonica, Carla Osorio, Javier Tejedor-Tejada, Javier Sanz, Lourdes M. Cuadrado, Marta Moorjani, Rajesh Gianchandani Suter, Michel Borbély, Yves Barajas-Gamboa, Juan S. Kroh, Matthew Kisiel, Aaron P. Kamocka, Anna Immanuel, Arul Sgromo, Bruno Gopinath, Bussa Khoo, David Mukherjee, Samrat Pournaras, Dimitrios Underwood, Tim Griffiths, Ewen A. Miller, Glenn V. Jaretzke, Helen Dmitrewski, Jan Gillies, Richard S. Singhal, Rishi Preston, Shaun R. Robinson, Steven John Hawkins, William J. Adamo, Marco El Kalaawy, Mohamed Gossage, James Crawford, Christopher B. Jaruvongvanich, Veeravich |
| description | Bariatric surgery can influence the presentation, diagnosis, and management of gastrointestinal cancers. Esophagogastric (EG) malignancies in patients who have had a prior bariatric procedure have not been fully characterized.
To characterize EG malignancies after bariatric procedures.
University Hospital, United Kingdom.
We performed a retrospective, multicenter observational study of patients with EG malignancies after bariatric surgery to characterize this condition.
This study includes 170 patients from 75 centers in 25 countries who underwent bariatric procedures between 1985 and 2020. At the time of the bariatric procedure, the mean age was 50.2 ± 10 years, and the mean weight 128.8 ± 28.9 kg. Women composed 57.3% (n = 98) of the population. Most (n = 64) patients underwent a Roux-en-Y gastric bypass (RYGB) followed by adjustable gastric band (AGB; n = 46) and sleeve gastrectomy (SG; n = 43). Time to cancer diagnosis after bariatric surgery was 9.5 ± 7.4 years, and mean weight at diagnosis was 87.4 ± 21.9 kg. The time lag was 5.9 ± 4.1 years after SG compared to 9.4 ± 7.1 years after RYGB and 10.5 ± 5.7 years after AGB. One third of patients presented with metastatic disease. The majority of tumors were adenocarcinoma (82.9%). Approximately 1 in 5 patients underwent palliative treatment from the outset. Time from diagnosis to mortality was under 1 year for most patients who died over the intervening period.
The Oesophago-Gastric Malignancies After Obesity/Bariatric Surgery study presents the largest series to date of patients developing EG malignancies after bariatric surgery and attempts to characterize this condition.
▪This is the largest series of patients developing OG cancer after bariatric surgery.▪OG cancers were diagnosed at a mean of 9.5 ± 7.4 years (range 1 – 44 years) from BS.▪One-third of the patients presented with distant metastasis at the time of diagnosis.▪Approximately 1 in 5 patients underwent palliative treatment. |
| doi_str_mv | 10.1016/j.soard.2021.11.024 |
| format | Article |
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Zakeri, Roxanna ; Abouelazayem, Mohamed ; Shin, Thomas H. ; Aminian, Ali ; Abu Dayyeh, Barham K. ; Wee, Melissa Y. ; Fischer, Laura ; Daams, Freek ; Mahawar, Kamal ; Agustin, Cataldo ; Fuente, Ignacio ; Carbajo, Miguel ; Cal, Patricio ; Chisholm, Jacob ; Tan, Michael H.L. ; Gan, Philip ; Gananadha, Sivakumar ; Felsenreich, Daniel M. ; Prager, Gerhard ; Matthys, Chris ; Himpens, Jacques M. ; Focquet, Marc A.M.R.M. ; Ramos, Almino ; Nato, Manoel Galvano ; Vidal, Thiago ; Andalib, Amin ; Siblini, Aya ; Ferri, Lorenzo ; Abdarabo, Lina ; Pescarus, Radu ; Yang, Wah ; Hamed, Hosam ; Bergeat, Damien ; Marie, De Montrichard ; Martini, Francesco ; Regis, François ; Genser, Laurent ; Skalli, Mehdi ; Nedelcu, Marius ; Smejkal, Milan ; Kassir, Radwan ; Nicolas, Regenet ; Stier, Christine ; Kermansaravi, Mohammad ; Raziel, Asnat ; Sakran, Nasser ; Oldani, Alberto ; Boru, Cristian Eugeniu ; Mécheri, Fouzia ; Ciccarese, Francesca ; Cesana, Giovanni Carlo ; Musella, Mario ; Foletto, Mirto ; Auricchio, Pasquale ; Olmi, Stefano ; Seki, Yosuke ; Van 'T Hof, Gerhard ; Hart, Judith W.H. ; Van De Sande, Justin S.L. ; Takkenberg, Marijn ; Snoekx, Rob ; Plat, Victor D. ; Kalinowski, Piotr ; Nabais, Celso ; Al-Bahrani, Ahmed Z. ; Al Zoubi, Mohammad ; Bettonica, Carla ; Osorio, Javier ; Tejedor-Tejada, Javier ; Sanz, Lourdes M. ; Cuadrado, Marta ; Moorjani, Rajesh Gianchandani ; Suter, Michel ; Borbély, Yves ; Barajas-Gamboa, Juan S. ; Kroh, Matthew ; Kisiel, Aaron P. ; Kamocka, Anna ; Immanuel, Arul ; Sgromo, Bruno ; Gopinath, Bussa ; Khoo, David ; Mukherjee, Samrat ; Pournaras, Dimitrios ; Underwood, Tim ; Griffiths, Ewen A. ; Miller, Glenn V. ; Jaretzke, Helen ; Dmitrewski, Jan ; Gillies, Richard S. ; Singhal, Rishi ; Preston, Shaun R. ; Robinson, Steven John ; Hawkins, William J. ; Adamo, Marco ; El Kalaawy, Mohamed ; Gossage, James ; Crawford, Christopher B. ; Jaruvongvanich, Veeravich</creator><creatorcontrib>Parmar, Chetan ; Zakeri, Roxanna ; Abouelazayem, Mohamed ; Shin, Thomas H. ; Aminian, Ali ; Abu Dayyeh, Barham K. ; Wee, Melissa Y. ; Fischer, Laura ; Daams, Freek ; Mahawar, Kamal ; Agustin, Cataldo ; Fuente, Ignacio ; Carbajo, Miguel ; Cal, Patricio ; Chisholm, Jacob ; Tan, Michael H.L. ; Gan, Philip ; Gananadha, Sivakumar ; Felsenreich, Daniel M. ; Prager, Gerhard ; Matthys, Chris ; Himpens, Jacques M. ; Focquet, Marc A.M.R.M. ; Ramos, Almino ; Nato, Manoel Galvano ; Vidal, Thiago ; Andalib, Amin ; Siblini, Aya ; Ferri, Lorenzo ; Abdarabo, Lina ; Pescarus, Radu ; Yang, Wah ; Hamed, Hosam ; Bergeat, Damien ; Marie, De Montrichard ; Martini, Francesco ; Regis, François ; Genser, Laurent ; Skalli, Mehdi ; Nedelcu, Marius ; Smejkal, Milan ; Kassir, Radwan ; Nicolas, Regenet ; Stier, Christine ; Kermansaravi, Mohammad ; Raziel, Asnat ; Sakran, Nasser ; Oldani, Alberto ; Boru, Cristian Eugeniu ; Mécheri, Fouzia ; Ciccarese, Francesca ; Cesana, Giovanni Carlo ; Musella, Mario ; Foletto, Mirto ; Auricchio, Pasquale ; Olmi, Stefano ; Seki, Yosuke ; Van 'T Hof, Gerhard ; Hart, Judith W.H. ; Van De Sande, Justin S.L. ; Takkenberg, Marijn ; Snoekx, Rob ; Plat, Victor D. ; Kalinowski, Piotr ; Nabais, Celso ; Al-Bahrani, Ahmed Z. ; Al Zoubi, Mohammad ; Bettonica, Carla ; Osorio, Javier ; Tejedor-Tejada, Javier ; Sanz, Lourdes M. ; Cuadrado, Marta ; Moorjani, Rajesh Gianchandani ; Suter, Michel ; Borbély, Yves ; Barajas-Gamboa, Juan S. ; Kroh, Matthew ; Kisiel, Aaron P. ; Kamocka, Anna ; Immanuel, Arul ; Sgromo, Bruno ; Gopinath, Bussa ; Khoo, David ; Mukherjee, Samrat ; Pournaras, Dimitrios ; Underwood, Tim ; Griffiths, Ewen A. ; Miller, Glenn V. ; Jaretzke, Helen ; Dmitrewski, Jan ; Gillies, Richard S. ; Singhal, Rishi ; Preston, Shaun R. ; Robinson, Steven John ; Hawkins, William J. ; Adamo, Marco ; El Kalaawy, Mohamed ; Gossage, James ; Crawford, Christopher B. ; Jaruvongvanich, Veeravich ; OGMOS Study Group</creatorcontrib><description>Bariatric surgery can influence the presentation, diagnosis, and management of gastrointestinal cancers. Esophagogastric (EG) malignancies in patients who have had a prior bariatric procedure have not been fully characterized.
To characterize EG malignancies after bariatric procedures.
University Hospital, United Kingdom.
We performed a retrospective, multicenter observational study of patients with EG malignancies after bariatric surgery to characterize this condition.
This study includes 170 patients from 75 centers in 25 countries who underwent bariatric procedures between 1985 and 2020. At the time of the bariatric procedure, the mean age was 50.2 ± 10 years, and the mean weight 128.8 ± 28.9 kg. Women composed 57.3% (n = 98) of the population. Most (n = 64) patients underwent a Roux-en-Y gastric bypass (RYGB) followed by adjustable gastric band (AGB; n = 46) and sleeve gastrectomy (SG; n = 43). Time to cancer diagnosis after bariatric surgery was 9.5 ± 7.4 years, and mean weight at diagnosis was 87.4 ± 21.9 kg. The time lag was 5.9 ± 4.1 years after SG compared to 9.4 ± 7.1 years after RYGB and 10.5 ± 5.7 years after AGB. One third of patients presented with metastatic disease. The majority of tumors were adenocarcinoma (82.9%). Approximately 1 in 5 patients underwent palliative treatment from the outset. Time from diagnosis to mortality was under 1 year for most patients who died over the intervening period.
The Oesophago-Gastric Malignancies After Obesity/Bariatric Surgery study presents the largest series to date of patients developing EG malignancies after bariatric surgery and attempts to characterize this condition.
▪This is the largest series of patients developing OG cancer after bariatric surgery.▪OG cancers were diagnosed at a mean of 9.5 ± 7.4 years (range 1 – 44 years) from BS.▪One-third of the patients presented with distant metastasis at the time of diagnosis.▪Approximately 1 in 5 patients underwent palliative treatment.</description><identifier>ISSN: 1550-7289</identifier><identifier>EISSN: 1878-7533</identifier><identifier>DOI: 10.1016/j.soard.2021.11.024</identifier><identifier>PMID: 35065887</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adult ; Bariatric surgery ; Bariatric Surgery - adverse effects ; Bariatric Surgery - methods ; Esophageal cancer ; Esophagogastric cancer ; Female ; Gastrectomy - adverse effects ; Gastrectomy - methods ; Gastric Bypass - adverse effects ; Gastric Bypass - methods ; Gastric cancer ; Humans ; Metabolic surgery ; Middle Aged ; Obesity, Morbid - surgery ; Retrospective Studies ; Stomach Neoplasms - epidemiology ; Stomach Neoplasms - etiology ; Stomach Neoplasms - surgery ; Treatment Outcome</subject><ispartof>Surgery for obesity and related diseases, 2022-04, Vol.18 (4), p.464-472</ispartof><rights>2021 American Society for Bariatric Surgery</rights><rights>Copyright © 2021 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c432t-511487dddd45ba12ecec8ad6896ec0d697c832fd7b9782cfe5c50024a6c70e973</citedby><cites>FETCH-LOGICAL-c432t-511487dddd45ba12ecec8ad6896ec0d697c832fd7b9782cfe5c50024a6c70e973</cites><orcidid>0000-0003-2551-3462 ; 0000-0001-8084-7225 ; 0000-0002-6801-8974 ; 0000-0001-8099-994X ; 0000-0002-1238-6524 ; 0000-0001-6323-6342 ; 0000-0001-7460-3283 ; 0000-0003-1286-5450 ; 0000-0001-5756-9917</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S1550728921005694$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35065887$$D View this record in 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M.</creatorcontrib><creatorcontrib>Prager, Gerhard</creatorcontrib><creatorcontrib>Matthys, Chris</creatorcontrib><creatorcontrib>Himpens, Jacques M.</creatorcontrib><creatorcontrib>Focquet, Marc A.M.R.M.</creatorcontrib><creatorcontrib>Ramos, Almino</creatorcontrib><creatorcontrib>Nato, Manoel Galvano</creatorcontrib><creatorcontrib>Vidal, Thiago</creatorcontrib><creatorcontrib>Andalib, Amin</creatorcontrib><creatorcontrib>Siblini, Aya</creatorcontrib><creatorcontrib>Ferri, Lorenzo</creatorcontrib><creatorcontrib>Abdarabo, Lina</creatorcontrib><creatorcontrib>Pescarus, Radu</creatorcontrib><creatorcontrib>Yang, Wah</creatorcontrib><creatorcontrib>Hamed, Hosam</creatorcontrib><creatorcontrib>Bergeat, Damien</creatorcontrib><creatorcontrib>Marie, De Montrichard</creatorcontrib><creatorcontrib>Martini, Francesco</creatorcontrib><creatorcontrib>Regis, François</creatorcontrib><creatorcontrib>Genser, Laurent</creatorcontrib><creatorcontrib>Skalli, 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Anna</creatorcontrib><creatorcontrib>Immanuel, Arul</creatorcontrib><creatorcontrib>Sgromo, Bruno</creatorcontrib><creatorcontrib>Gopinath, Bussa</creatorcontrib><creatorcontrib>Khoo, David</creatorcontrib><creatorcontrib>Mukherjee, Samrat</creatorcontrib><creatorcontrib>Pournaras, Dimitrios</creatorcontrib><creatorcontrib>Underwood, Tim</creatorcontrib><creatorcontrib>Griffiths, Ewen A.</creatorcontrib><creatorcontrib>Miller, Glenn V.</creatorcontrib><creatorcontrib>Jaretzke, Helen</creatorcontrib><creatorcontrib>Dmitrewski, Jan</creatorcontrib><creatorcontrib>Gillies, Richard S.</creatorcontrib><creatorcontrib>Singhal, Rishi</creatorcontrib><creatorcontrib>Preston, Shaun R.</creatorcontrib><creatorcontrib>Robinson, Steven John</creatorcontrib><creatorcontrib>Hawkins, William J.</creatorcontrib><creatorcontrib>Adamo, Marco</creatorcontrib><creatorcontrib>El Kalaawy, Mohamed</creatorcontrib><creatorcontrib>Gossage, James</creatorcontrib><creatorcontrib>Crawford, Christopher B.</creatorcontrib><creatorcontrib>Jaruvongvanich, Veeravich</creatorcontrib><creatorcontrib>OGMOS Study Group</creatorcontrib><title>Esophageal and gastric malignancies after bariatric surgery: a retrospective global study</title><title>Surgery for obesity and related diseases</title><addtitle>Surg Obes Relat Dis</addtitle><description>Bariatric surgery can influence the presentation, diagnosis, and management of gastrointestinal cancers. Esophagogastric (EG) malignancies in patients who have had a prior bariatric procedure have not been fully characterized.
To characterize EG malignancies after bariatric procedures.
University Hospital, United Kingdom.
We performed a retrospective, multicenter observational study of patients with EG malignancies after bariatric surgery to characterize this condition.
This study includes 170 patients from 75 centers in 25 countries who underwent bariatric procedures between 1985 and 2020. At the time of the bariatric procedure, the mean age was 50.2 ± 10 years, and the mean weight 128.8 ± 28.9 kg. Women composed 57.3% (n = 98) of the population. Most (n = 64) patients underwent a Roux-en-Y gastric bypass (RYGB) followed by adjustable gastric band (AGB; n = 46) and sleeve gastrectomy (SG; n = 43). Time to cancer diagnosis after bariatric surgery was 9.5 ± 7.4 years, and mean weight at diagnosis was 87.4 ± 21.9 kg. The time lag was 5.9 ± 4.1 years after SG compared to 9.4 ± 7.1 years after RYGB and 10.5 ± 5.7 years after AGB. One third of patients presented with metastatic disease. The majority of tumors were adenocarcinoma (82.9%). Approximately 1 in 5 patients underwent palliative treatment from the outset. Time from diagnosis to mortality was under 1 year for most patients who died over the intervening period.
The Oesophago-Gastric Malignancies After Obesity/Bariatric Surgery study presents the largest series to date of patients developing EG malignancies after bariatric surgery and attempts to characterize this condition.
▪This is the largest series of patients developing OG cancer after bariatric surgery.▪OG cancers were diagnosed at a mean of 9.5 ± 7.4 years (range 1 – 44 years) from BS.▪One-third of the patients presented with distant metastasis at the time of diagnosis.▪Approximately 1 in 5 patients underwent palliative treatment.</description><subject>Adult</subject><subject>Bariatric surgery</subject><subject>Bariatric Surgery - adverse effects</subject><subject>Bariatric Surgery - methods</subject><subject>Esophageal cancer</subject><subject>Esophagogastric cancer</subject><subject>Female</subject><subject>Gastrectomy - adverse effects</subject><subject>Gastrectomy - methods</subject><subject>Gastric Bypass - adverse effects</subject><subject>Gastric Bypass - methods</subject><subject>Gastric cancer</subject><subject>Humans</subject><subject>Metabolic surgery</subject><subject>Middle Aged</subject><subject>Obesity, Morbid - surgery</subject><subject>Retrospective Studies</subject><subject>Stomach Neoplasms - epidemiology</subject><subject>Stomach Neoplasms - etiology</subject><subject>Stomach Neoplasms - surgery</subject><subject>Treatment Outcome</subject><issn>1550-7289</issn><issn>1878-7533</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMtKxTAQhoMo3p9AkC7dtObSNKngQsQbCG504SpMk2nNoac9Jq1w3t7oUZfOZgbmn_lnPkJOGC0YZdX5oogjBFdwylnBWEF5uUX2mVY6V1KI7VRLSXPFdb1HDmJcUCoqqfgu2ROSVlJrtU9eb-K4eoMOoc9gcFkHcQreZkvofTfAYD3GDNoJQ9ZA8PDdjHPoMKwvMsgCTmGMK7ST_8Cs68cmLYrT7NZHZKeFPuLxTz4kL7c3z9f3-ePT3cP11WNuS8GnXDJWauVSlLIBxtGi1eAqXVdoqatqZbXgrVNNrTS3LUoraXoVKqso1kockrPN3lUY32eMk1n6aLHvYcBxjoZXnJdKCCqTVGykNt0cA7ZmFfwSwtowar6YmoX5Zmq-mBrGTDJKU6c_BnOzRPc38wsxCS43AkxvfngMJiZsg0XnQwJj3Oj_NfgETSCKcg</recordid><startdate>202204</startdate><enddate>202204</enddate><creator>Parmar, Chetan</creator><creator>Zakeri, Roxanna</creator><creator>Abouelazayem, Mohamed</creator><creator>Shin, 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Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-2551-3462</orcidid><orcidid>https://orcid.org/0000-0001-8084-7225</orcidid><orcidid>https://orcid.org/0000-0002-6801-8974</orcidid><orcidid>https://orcid.org/0000-0001-8099-994X</orcidid><orcidid>https://orcid.org/0000-0002-1238-6524</orcidid><orcidid>https://orcid.org/0000-0001-6323-6342</orcidid><orcidid>https://orcid.org/0000-0001-7460-3283</orcidid><orcidid>https://orcid.org/0000-0003-1286-5450</orcidid><orcidid>https://orcid.org/0000-0001-5756-9917</orcidid></search><sort><creationdate>202204</creationdate><title>Esophageal and gastric malignancies after bariatric surgery: a retrospective global study</title><author>Parmar, Chetan ; Zakeri, Roxanna ; Abouelazayem, Mohamed ; Shin, Thomas H. ; Aminian, Ali ; Abu Dayyeh, Barham K. ; Wee, Melissa Y. ; Fischer, Laura ; Daams, Freek ; Mahawar, Kamal ; Agustin, Cataldo ; Fuente, Ignacio ; Carbajo, Miguel ; Cal, Patricio ; Chisholm, Jacob ; Tan, Michael H.L. ; Gan, Philip ; Gananadha, Sivakumar ; Felsenreich, Daniel M. ; Prager, Gerhard ; Matthys, Chris ; Himpens, Jacques M. ; Focquet, Marc A.M.R.M. ; Ramos, Almino ; Nato, Manoel Galvano ; Vidal, Thiago ; Andalib, Amin ; Siblini, Aya ; Ferri, Lorenzo ; Abdarabo, Lina ; Pescarus, Radu ; Yang, Wah ; Hamed, Hosam ; Bergeat, Damien ; Marie, De Montrichard ; Martini, Francesco ; Regis, François ; Genser, Laurent ; Skalli, Mehdi ; Nedelcu, Marius ; Smejkal, Milan ; Kassir, Radwan ; Nicolas, Regenet ; Stier, Christine ; Kermansaravi, Mohammad ; Raziel, Asnat ; Sakran, Nasser ; Oldani, Alberto ; Boru, Cristian Eugeniu ; Mécheri, Fouzia ; Ciccarese, Francesca ; Cesana, Giovanni Carlo ; Musella, Mario ; Foletto, Mirto ; Auricchio, Pasquale ; Olmi, Stefano ; Seki, Yosuke ; Van 'T Hof, Gerhard ; Hart, Judith W.H. ; Van De Sande, Justin S.L. ; Takkenberg, Marijn ; Snoekx, Rob ; Plat, Victor D. ; Kalinowski, Piotr ; Nabais, Celso ; Al-Bahrani, Ahmed Z. ; Al Zoubi, Mohammad ; Bettonica, Carla ; Osorio, Javier ; Tejedor-Tejada, Javier ; Sanz, Lourdes M. ; Cuadrado, Marta ; Moorjani, Rajesh Gianchandani ; Suter, Michel ; Borbély, Yves ; Barajas-Gamboa, Juan S. ; Kroh, Matthew ; Kisiel, Aaron P. ; Kamocka, Anna ; Immanuel, Arul ; Sgromo, Bruno ; Gopinath, Bussa ; Khoo, David ; Mukherjee, Samrat ; Pournaras, Dimitrios ; Underwood, Tim ; Griffiths, Ewen A. ; Miller, Glenn V. ; Jaretzke, Helen ; Dmitrewski, Jan ; Gillies, Richard S. ; Singhal, Rishi ; Preston, Shaun R. ; Robinson, Steven John ; Hawkins, William J. ; Adamo, Marco ; El Kalaawy, Mohamed ; Gossage, James ; Crawford, Christopher B. ; Jaruvongvanich, Veeravich</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c432t-511487dddd45ba12ecec8ad6896ec0d697c832fd7b9782cfe5c50024a6c70e973</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Adult</topic><topic>Bariatric surgery</topic><topic>Bariatric Surgery - adverse effects</topic><topic>Bariatric Surgery - methods</topic><topic>Esophageal cancer</topic><topic>Esophagogastric cancer</topic><topic>Female</topic><topic>Gastrectomy - adverse effects</topic><topic>Gastrectomy - methods</topic><topic>Gastric Bypass - adverse effects</topic><topic>Gastric Bypass - methods</topic><topic>Gastric cancer</topic><topic>Humans</topic><topic>Metabolic surgery</topic><topic>Middle Aged</topic><topic>Obesity, Morbid - surgery</topic><topic>Retrospective Studies</topic><topic>Stomach Neoplasms - epidemiology</topic><topic>Stomach Neoplasms - etiology</topic><topic>Stomach Neoplasms - surgery</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Parmar, Chetan</creatorcontrib><creatorcontrib>Zakeri, Roxanna</creatorcontrib><creatorcontrib>Abouelazayem, Mohamed</creatorcontrib><creatorcontrib>Shin, Thomas H.</creatorcontrib><creatorcontrib>Aminian, Ali</creatorcontrib><creatorcontrib>Abu Dayyeh, Barham K.</creatorcontrib><creatorcontrib>Wee, Melissa Y.</creatorcontrib><creatorcontrib>Fischer, Laura</creatorcontrib><creatorcontrib>Daams, Freek</creatorcontrib><creatorcontrib>Mahawar, Kamal</creatorcontrib><creatorcontrib>Agustin, Cataldo</creatorcontrib><creatorcontrib>Fuente, Ignacio</creatorcontrib><creatorcontrib>Carbajo, Miguel</creatorcontrib><creatorcontrib>Cal, Patricio</creatorcontrib><creatorcontrib>Chisholm, Jacob</creatorcontrib><creatorcontrib>Tan, Michael H.L.</creatorcontrib><creatorcontrib>Gan, Philip</creatorcontrib><creatorcontrib>Gananadha, 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Gerhard</creatorcontrib><creatorcontrib>Hart, Judith W.H.</creatorcontrib><creatorcontrib>Van De Sande, Justin S.L.</creatorcontrib><creatorcontrib>Takkenberg, Marijn</creatorcontrib><creatorcontrib>Snoekx, Rob</creatorcontrib><creatorcontrib>Plat, Victor D.</creatorcontrib><creatorcontrib>Kalinowski, Piotr</creatorcontrib><creatorcontrib>Nabais, Celso</creatorcontrib><creatorcontrib>Al-Bahrani, Ahmed Z.</creatorcontrib><creatorcontrib>Al Zoubi, Mohammad</creatorcontrib><creatorcontrib>Bettonica, Carla</creatorcontrib><creatorcontrib>Osorio, Javier</creatorcontrib><creatorcontrib>Tejedor-Tejada, Javier</creatorcontrib><creatorcontrib>Sanz, Lourdes M.</creatorcontrib><creatorcontrib>Cuadrado, Marta</creatorcontrib><creatorcontrib>Moorjani, Rajesh Gianchandani</creatorcontrib><creatorcontrib>Suter, Michel</creatorcontrib><creatorcontrib>Borbély, Yves</creatorcontrib><creatorcontrib>Barajas-Gamboa, Juan S.</creatorcontrib><creatorcontrib>Kroh, 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Mohamed</creatorcontrib><creatorcontrib>Gossage, James</creatorcontrib><creatorcontrib>Crawford, Christopher B.</creatorcontrib><creatorcontrib>Jaruvongvanich, Veeravich</creatorcontrib><creatorcontrib>OGMOS Study Group</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Surgery for obesity and related diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Parmar, Chetan</au><au>Zakeri, Roxanna</au><au>Abouelazayem, Mohamed</au><au>Shin, Thomas H.</au><au>Aminian, Ali</au><au>Abu Dayyeh, Barham K.</au><au>Wee, Melissa Y.</au><au>Fischer, Laura</au><au>Daams, Freek</au><au>Mahawar, Kamal</au><au>Agustin, Cataldo</au><au>Fuente, Ignacio</au><au>Carbajo, Miguel</au><au>Cal, Patricio</au><au>Chisholm, Jacob</au><au>Tan, Michael H.L.</au><au>Gan, Philip</au><au>Gananadha, Sivakumar</au><au>Felsenreich, Daniel M.</au><au>Prager, Gerhard</au><au>Matthys, Chris</au><au>Himpens, Jacques M.</au><au>Focquet, Marc A.M.R.M.</au><au>Ramos, Almino</au><au>Nato, Manoel Galvano</au><au>Vidal, Thiago</au><au>Andalib, Amin</au><au>Siblini, Aya</au><au>Ferri, Lorenzo</au><au>Abdarabo, Lina</au><au>Pescarus, Radu</au><au>Yang, Wah</au><au>Hamed, Hosam</au><au>Bergeat, Damien</au><au>Marie, De Montrichard</au><au>Martini, Francesco</au><au>Regis, François</au><au>Genser, Laurent</au><au>Skalli, Mehdi</au><au>Nedelcu, Marius</au><au>Smejkal, Milan</au><au>Kassir, Radwan</au><au>Nicolas, Regenet</au><au>Stier, Christine</au><au>Kermansaravi, Mohammad</au><au>Raziel, Asnat</au><au>Sakran, Nasser</au><au>Oldani, Alberto</au><au>Boru, Cristian Eugeniu</au><au>Mécheri, Fouzia</au><au>Ciccarese, Francesca</au><au>Cesana, Giovanni Carlo</au><au>Musella, Mario</au><au>Foletto, Mirto</au><au>Auricchio, Pasquale</au><au>Olmi, Stefano</au><au>Seki, Yosuke</au><au>Van 'T Hof, Gerhard</au><au>Hart, Judith W.H.</au><au>Van De Sande, Justin S.L.</au><au>Takkenberg, Marijn</au><au>Snoekx, Rob</au><au>Plat, Victor D.</au><au>Kalinowski, Piotr</au><au>Nabais, Celso</au><au>Al-Bahrani, Ahmed Z.</au><au>Al Zoubi, Mohammad</au><au>Bettonica, Carla</au><au>Osorio, Javier</au><au>Tejedor-Tejada, Javier</au><au>Sanz, Lourdes M.</au><au>Cuadrado, Marta</au><au>Moorjani, Rajesh Gianchandani</au><au>Suter, Michel</au><au>Borbély, Yves</au><au>Barajas-Gamboa, Juan S.</au><au>Kroh, Matthew</au><au>Kisiel, Aaron P.</au><au>Kamocka, Anna</au><au>Immanuel, Arul</au><au>Sgromo, Bruno</au><au>Gopinath, Bussa</au><au>Khoo, David</au><au>Mukherjee, Samrat</au><au>Pournaras, Dimitrios</au><au>Underwood, Tim</au><au>Griffiths, Ewen A.</au><au>Miller, Glenn V.</au><au>Jaretzke, Helen</au><au>Dmitrewski, Jan</au><au>Gillies, Richard S.</au><au>Singhal, Rishi</au><au>Preston, Shaun R.</au><au>Robinson, Steven John</au><au>Hawkins, William J.</au><au>Adamo, Marco</au><au>El Kalaawy, Mohamed</au><au>Gossage, James</au><au>Crawford, Christopher B.</au><au>Jaruvongvanich, Veeravich</au><aucorp>OGMOS Study Group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Esophageal and gastric malignancies after bariatric surgery: a retrospective global study</atitle><jtitle>Surgery for obesity and related diseases</jtitle><addtitle>Surg Obes Relat Dis</addtitle><date>2022-04</date><risdate>2022</risdate><volume>18</volume><issue>4</issue><spage>464</spage><epage>472</epage><pages>464-472</pages><issn>1550-7289</issn><eissn>1878-7533</eissn><abstract>Bariatric surgery can influence the presentation, diagnosis, and management of gastrointestinal cancers. Esophagogastric (EG) malignancies in patients who have had a prior bariatric procedure have not been fully characterized.
To characterize EG malignancies after bariatric procedures.
University Hospital, United Kingdom.
We performed a retrospective, multicenter observational study of patients with EG malignancies after bariatric surgery to characterize this condition.
This study includes 170 patients from 75 centers in 25 countries who underwent bariatric procedures between 1985 and 2020. At the time of the bariatric procedure, the mean age was 50.2 ± 10 years, and the mean weight 128.8 ± 28.9 kg. Women composed 57.3% (n = 98) of the population. Most (n = 64) patients underwent a Roux-en-Y gastric bypass (RYGB) followed by adjustable gastric band (AGB; n = 46) and sleeve gastrectomy (SG; n = 43). Time to cancer diagnosis after bariatric surgery was 9.5 ± 7.4 years, and mean weight at diagnosis was 87.4 ± 21.9 kg. The time lag was 5.9 ± 4.1 years after SG compared to 9.4 ± 7.1 years after RYGB and 10.5 ± 5.7 years after AGB. One third of patients presented with metastatic disease. The majority of tumors were adenocarcinoma (82.9%). Approximately 1 in 5 patients underwent palliative treatment from the outset. Time from diagnosis to mortality was under 1 year for most patients who died over the intervening period.
The Oesophago-Gastric Malignancies After Obesity/Bariatric Surgery study presents the largest series to date of patients developing EG malignancies after bariatric surgery and attempts to characterize this condition.
▪This is the largest series of patients developing OG cancer after bariatric surgery.▪OG cancers were diagnosed at a mean of 9.5 ± 7.4 years (range 1 – 44 years) from BS.▪One-third of the patients presented with distant metastasis at the time of diagnosis.▪Approximately 1 in 5 patients underwent palliative treatment.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>35065887</pmid><doi>10.1016/j.soard.2021.11.024</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0003-2551-3462</orcidid><orcidid>https://orcid.org/0000-0001-8084-7225</orcidid><orcidid>https://orcid.org/0000-0002-6801-8974</orcidid><orcidid>https://orcid.org/0000-0001-8099-994X</orcidid><orcidid>https://orcid.org/0000-0002-1238-6524</orcidid><orcidid>https://orcid.org/0000-0001-6323-6342</orcidid><orcidid>https://orcid.org/0000-0001-7460-3283</orcidid><orcidid>https://orcid.org/0000-0003-1286-5450</orcidid><orcidid>https://orcid.org/0000-0001-5756-9917</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1550-7289 |
| ispartof | Surgery for obesity and related diseases, 2022-04, Vol.18 (4), p.464-472 |
| issn | 1550-7289 1878-7533 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2622473305 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adult Bariatric surgery Bariatric Surgery - adverse effects Bariatric Surgery - methods Esophageal cancer Esophagogastric cancer Female Gastrectomy - adverse effects Gastrectomy - methods Gastric Bypass - adverse effects Gastric Bypass - methods Gastric cancer Humans Metabolic surgery Middle Aged Obesity, Morbid - surgery Retrospective Studies Stomach Neoplasms - epidemiology Stomach Neoplasms - etiology Stomach Neoplasms - surgery Treatment Outcome |
| title | Esophageal and gastric malignancies after bariatric surgery: a retrospective global study |
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