Beneficial effects of MgSO4 on TFAM, UPC3 and FNDC5 mRNA expressions in skeletal muscle of type 2 diabetic rats: a possible mechanism to improve insulin resistance

Background Hypomagnesemia has been associated with development of type 2 diabetes mellitus (T2DM) and its complications. Irisin has beneficial effects on glucose uptake and improves hepatic glucose and lipid metabolism. In this study, we aimed to evaluate the effects of long-term treatment of MgSO 4...

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Veröffentlicht in:	Molecular biology reports 2022-04, Vol.49 (4), p.2795-2803
Hauptverfasser:	Yazdanimoghaddam, Farzaneh, Aghaei, Mahmoud, Ghasemi, Maedeh, Soltani, Nepton, Rezazadeh, Hossein, Zadhoush, Fouzieh
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Anatomy Animal Biochemistry Biomedical and Life Sciences Diabetes Diabetes mellitus (non-insulin dependent) Dyslipidemia Fibronectin Gene expression Glucose metabolism High fat diet Histology Hyperlipidemia Hypomagnesemia Insulin Insulin resistance Life Sciences Lipid metabolism Liver Low density lipoprotein Mitochondria Morphology Musculoskeletal system Original Article Skeletal muscle Streptozocin
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