IQGAP1‐mediated mechanical signaling promotes the foreign body response to biomedical implants

The aim of this study was to further elucidate the molecular mechanisms that mediate pathologic foreign body response (FBR) to biomedical implants. The longevity of biomedical implants is limited by the FBR, which leads to implant failure and patient morbidity. Since the specific molecular mechanism...

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Veröffentlicht in:The FASEB journal 2022-02, Vol.36 (2), p.e22007-n/a
Hauptverfasser: Sivaraj, Dharshan, Padmanabhan, Jagannath, Chen, Kellen, Henn, Dominic, Noishiki, Chikage, Trotsyuk, Artem A., Kussie, Hudson C., Leeolou, Melissa C., Magbual, Noah J., Andrikopoulos, Sophia, Perrault, David P., Barrera, Janos A., Januszyk, Michael, Gurtner, Geoffrey C.
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Sprache:eng
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